DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7956 and Sh2d1b2

DIOPT Version :9

Sequence 1:	NP_001036740.2	Gene:	CG7956 / 42545	FlyBaseID:	FBgn0038890	Length:	1142	Species:	Drosophila melanogaster
Sequence 2:	NP_001028671.1	Gene:	Sh2d1b2 / 545378	MGIID:	3622649	Length:	132	Species:	Mus musculus

Alignment Length:	170	Identity:	37/170 - (21%)
Similarity:	58/170 - (34%)	Gaps:	57/170 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 LPIIQGFMQVENCVIGNECFTLALVSRRSRHRAGTRYKRRGVDEKGNCANYV--ETEQILSFRHH 317
            ||...|      |:...||..|.|              :.|||     .|::  ::|.:......
Mouse     3 LPYYHG------CLTKRECEALLL--------------KGGVD-----GNFLIRDSESVPGALCL 42

  Fly   318 QLSFTQVRGSVPIYWSQPGYKYRPPPRLDRGVAETQQAFELHFTKELETYGRVCIVNLVEQSGKE 382
            .:||.::..:..|:..:.|| ||         .||:.:..           :....||.|...|.
Mouse    43 CVSFKKLVYNYRIFREKNGY-YR---------IETEPSTP-----------KTIFPNLEELISKF 86

  Fly   383 KTIGDAYADHVIKLNNDRLIYVTFDFHDYCRGMRFENVSA 422
            ||.|...   |:.|:|..:      ...:|.|.|..|:.|
Mouse    87 KTPGQGM---VVHLSNPIM------RSGFCPGARRLNLEA 117

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7956	NP_001036740.2	Syja_N	174..413	CDD:280532	32/159 (20%)
		COG5329	<197..586	CDD:227637	37/170 (22%)
		hSac2	663..768	CDD:289241
Sh2d1b2	NP_001028671.1	SH2_SAP1	1..103	CDD:198205	32/154 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836231
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930