Protein Alignment CG7956 and inppl1b

DIOPT Version :9

• Sequence 1: NP_001036740.2
• Gene: CG7956 / 42545
• FlyBaseID: FBgn0038890
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: NP_001034224.2
• Gene: inppl1b / 368433
• ZFINID: ZDB-GENE-030616-75
• Length: 1226
• Species: Danio rerio
• Alignment Length: 1243
• Identity: 224/1243 - (18%)
• Similarity: 403/1243 - (32%)
• Gaps: 404/1243 - (32%)

  Fly    20 WWHR-----RTSEFSIKAGWDLS-SVDDIECIGVTHGIVGVISLPNVYEPH------------LV 66
            |:||     |..|....||.|.| .|.|.|      .:.|..:|..:::.|            |:
Zfish     6 WYHRDISRVRAEELLAHAGIDGSFLVRDSE------SVPGAYALCLLFQRHVHTYRILPDADGLL 64

  Fly    67 VVKEASAV--------------------GVLYPPHLVYKI--KSICILSADDPDTDLPNCTKHTK 109
            .|:....|                    |::.|  |:|.:  :|.....:.|.|.:.|..|
Zfish    65 AVQATQGVQVNCFRTLGDLVLGYQNPNKGLVAP--LLYPVMRESEANDESSDGDDEKPGST---- 123

  Fly   110 SNQSTPTHSVSTSNNNNASVPSSGGGSSKSTKLFEGMNKTWGAVKSAGNTI---------KNTTQ 165
             ..::|..::|.:   ..|.|||   |:....|.:.:.:.  :..|.|..|         .|..:
Zfish   124 -FANSPPRTISPT---ATSPPSS---SAAPHLLLQRLQEL--SPNSVGCEIVSLLDEYLHGNVCK 179

  Fly   166 QAANLATKQVKSSVGIREPRHIERRITEELHKIFDET-------------DSFYFSFD------- 210
            ...||.    ..:.|::..:.|...|.:.||...|:|             .|.:.:|.
Zfish   180 DLENLK----GGASGLQHFQGILSHICDSLHSEIDQTLSSLETLAKVFDHPSGHLTFSTMQNTGK 240

  Fly   211 ----------------CDITNNLQRHEAKSEE----------SQSQPDERFFWNKHMIR------ 243
                            |::.::|::...|:.:          ..:.|.|.....|.:.|
Zfish   241 SPEENMDNLLQKLTTLCNLLSSLEKRVLKALQEAVANHNLSLQPATPPESIRAPKKLARPNPVHS 305

  Fly   244 ---DLINLNDKTWILPIIQGFM--QVENCVIGNECFTLALVSRRSRHRAGTRYKRRGVDEKGNCA 303
               .::....:|..:.|.:|.:  ..::...|.|..||..:.:..:.:.|....:..||.
Zfish   306 FQVKVVRYGRQTVSVDINEGVLLFDKKSGSFGVETVTLDRIVQLVKFQRGPAKLKMVVDS----- 365

  Fly   304 NYVETEQILSFRHHQLSFTQVRGSVPIYWSQPGYKYRPPPRLDRGVAETQQAFELHF--TKELET 366
                        ||.                       |||            ||.|  ||:.|.
Zfish   366 ------------HHN-----------------------PPR------------ELVFESTKKREA 383

  Fly   367 YGRVCIVNLVEQSGKEKTIGDAYADHVIKLN-------NDRLIYVTFDFHDYCRGMRF---ENVS 421
            :.|  ::.|::.:..:|:..|..:..|...|       .....:||      |.|:..   |::|
Zfish   384 FCR--LLQLMKTTHSQKSELDVISVFVGTWNMGGTPPPGSLQSWVT------CSGLGLTPDESIS 440

  Fly   422 AL---IDAVGPEAGAMGFHWRDQRGMICNQKSVFRVNCMDCLDRTNV------VQTA--IGKAVL 475
            :|   |.|||.:....|     :|....:.::..|.:       ||:      ||:.  |..||.
Zfish   441 SLPHDIYAVGTQDNPQG-----EREWAEHIRATLRTS-------TNIDYKQVAVQSLWNIRLAVF 493

  Fly   476 -----ESQLVKLGLSPPYTPIPEQLKSPFMVLWANNGDI-ISRQYAGTN--------------AL 520
                 |:::.::..:...|.:...|        .|.|.: :|..:.||:              ||
Zfish   494 VKPEHEARISQVNTASVKTGLGNTL--------GNKGAVGVSLLFNGTSMGFVNCHLTSGSDKAL 550

  Fly   521 KGDYT--------RTGERKISGMMKDGMNSANRFFIQNFADSFRQCIIDLMQGQLLRAEDLQEDE 577
            :.::.        ..||:::| .....:...:.|:..:.  ::|   :||....:|:....:|.|
Zfish   551 RRNHNFQDILRLLSLGEKQLS-TFDISLRFNHLFWCGDL--NYR---LDLDALDILKHVSKREFE 609

  Fly   578 VLSTILQILTPE--TRPPLHGYYNPGVLGPELQLLESIVTTSYYLARFKDSYRQATIDLMLGNQV 640
            .|....| ||.|  .|.....:....::.|.....|......|...::|.|          |.||
Zfish   610 ELMCADQ-LTRERHKRKAFFNFKEEKIMFPPTYRYERGSRDCYLWQKYKSS----------GVQV 663

  Fly   641 SSES-LSALGGQAGPDEN---------DGTENAEQAKLLVEDCRRLLLGTAQYPVGAWGLIDADP 695
            :..| ...:..::.|:.:         |....:|.:.:.           |.:.||...|.....
Zfish   664 NGPSWCDRVLWKSYPESHVICTSYGCTDDIFTSEHSPVF-----------ATFEVGVISLFPRTE 717

  Fly   696 SSGDINETEVDTILLLT-----------------DDCYIVAEYDSHLDKIVRFEKVQLTQVRLIE 743
            |..:....|::.|..:.                 ::....||.||...::..|.|:..:..:|.:
Zfish   718 SCSERASIELEAIEAIVKTSSKAKFFIEFHSRCLEEPRRSAENDSQYCEVPGFLKLGWSSKQLPK 782

  Fly   744 LGMHQQTKIFQGSAPAHLCLRLNYSVDEQEGYFHMFRSANLRFFNNMAYVIKTQEEV----AESM 804
            |  |......:.....||.|    ||...:| |..:....:........::.|.|..    .|.|
Zfish   783 L--HPVFLDLEHLRDQHLLL----SVKSCDG-FESYGECCVALRPTAGKLLDTFETCLTHRGEEM 840

  Fly   805 TSIVEMFRIALDNAGNTEVRYITGGVLQRRKSKLPTLDVPRGMPRNLSESQLVQLSSKALSNMAG 869
            .||...||:           |:.....:.|:.....|.:.:. .|.:.:.||...||.|.|..|.
Zfish   841 GSIRGRFRV-----------YVPPDRRRIRERVYEWLSIEKD-EREMMKDQLSPPSSSAFSIKAP 893

  Fly   870 QFSKLGQ----------------TFKKPQAHPSSLAATMNPQVMRQRDSEIESGQEAEKAVFTL- 917
            ..|.:..                .|:|.:..||::           ::|::..   |...|..|
Zfish   894 SASYVASPNSYTNPAYFIFEEMPVFRKAEEIPSTI-----------KESQVVC---ANNTVIQLP 944

  Fly   918 ---GRKHRNSNSASSTDTDEHD--NSL--YEPEVDSDVEIAMDKSNYN--ENAFLPSVGIVMGNQ 973
               |.......||..:|..|.:  .||  |:|..::..|::...|:|.  ....:||..   .||
Zfish   945 RVTGSHGHGKRSARRSDFTEIEIPGSLAPYKPSCETQSELSSTASSYQLFPGPHVPSTS---PNQ 1006

  Fly   974 KEDSPSSSDEIRHLEQKDSMC--------KTTEDVLTISITS--------VTDHVGLPTGL---L 1019
            :..:.||:..::....|::|.        |.|...:..|:.|        ..|:.|:..|.   :
Zfish  1007 RHTTHSSNSSLQLQSHKNNMAPDSELSGKKLTNSYMNHSVFSRDMHKEKVRQDYQGVHQGRPVPI 1071

  Fly  1020 ENAPAIRP 1027
            .|.|.:.|
Zfish  1072 RNGPKLYP 1079

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7956	NP_001036740.2	Syja_N	174..413	CDD:280532	45/304 (15%)
		COG5329	<197..586	CDD:227637	81/496 (16%)
		hSac2	663..768	CDD:289241	20/121 (17%)
inppl1b	NP_001034224.2	SH2_SHIP	2..104	CDD:198206	22/105 (21%)
		EEP	404..707	CDD:294334	62/356 (17%)
		SAM_superfamily	1165..1221	CDD:301707
		SAM	1165..1218	CDD:197735

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579696
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930