Protein Alignment sp3 and Ocrl

DIOPT Version :10

• Sequence 1: NP_001036740.2
• Gene: sp3 / 42545
• FlyBaseID: FBgn0038890
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: XP_558090.4
• Gene: Ocrl / 3291116
• VectorBaseID: AGAMI1_001352
• Length: 876
• Species: Anopheles gambiae
• Alignment Length: 635
• Identity: 116/635 - (18%)
• Similarity: 206/635 - (32%)
• Gaps: 239/635 - (37%)

  Fly   213 ITNNLQRH---EAKSEESQS--------QPDERFFWNKHMIRDLINLNDKT--WILPIIQG-FMQ 263
            :.||.|..   ...|.||.:        :|.|             :::|.|  .::||.:. |:.
Mosquito    34 VGNNFQNRLLVTVSSSESAALFSFSVSREPPE-------------SISDLTIVAVVPINESFFVN 85

  Fly   264 VENCV--IGNECFTLALVSRRSRHRAGTRYKRRGVDEKGNCANYVETEQILSFRHHQL-SFTQVR 325
            .|:..  :.:..||:.     |.::..|.|             |..||:|.:.:.|.| |...::
Mosquito    86 TESSFGSVSSHQFTVF-----SDNQPTTYY-------------YHATEEISAAKEHFLTSLKNLK 132

  Fly   326 GS---VPIYWSQPG-----YKYRPPPR------LDRGVAETQQA---FELHFTKELETYGRVCIV 373
            .|   ||::  .||     :.|:|...      :||.||:..||   .:..|.:||
Mosquito   133 ASYRAVPVH--SPGAFDWLHYYKPADERTGLLAIDRSVADGSQAPKTRDAKFREEL--------- 186

  Fly   374 NLVEQSGKEKTIGDAYADHVIKLNNDRLIYVTFDFHDYCRGMRFENVSALIDAVGPEAGAMGF-- 436
               |:...|.|:.:.|..:....|.:.....|.:..::.         |..|: .|:..|:||
Mosquito   187 ---ERRRHEYTVYEPYHVYTATWNVNGQTSETIELPEWL---------ATTDS-PPDIYAVGFQE 238

  Fly   437 -HWRDQRGMICNQKSVFRVNCMDCLDRTNV--VQTAIGKAVLESQLVKLGL----------SPPY 488
             .|..:: ::.|:..:         |||.|  |.:.:.|..:.::|..:.|          |..|
Mosquito   239 IEWTPEK-ILMNETKI---------DRTWVDKVMSGLHKGAIYTELASVRLVGMMLTVAVKSTIY 293

  Fly   489 TPIPEQLKSPF---MVLWANNG----------------------------------DIISRQYAG 516
            ..|.:.|.:..   .:.|.|.|                                  |.|.|:.:.
Mosquito   294 PKINDCLTAAVGTGTLKWGNKGGVGVSFKLNEALFCFVNTHLAAHTQEVERRNDDHDDIIRRMSF 358

  Fly   517 TNALK-------------GD--YTRTGERKISGMMKDGMNSANRFFIQNFADSFRQCIIDLMQGQ 566
            .|..:             ||  |...|..    :.::.:|..:|.:.|.:...  |..::..:.:
Mosquito   359 DNGFRMRSIDEHHHIFWIGDLNYRLDGPE----VSQEYVNRKDRDYNQLYQHD--QLYVEKRRNR 417

  Fly   567 LLRAEDLQEDEVLSTILQILTPETRPPLHGYYNPGV--------------------LGPELQLLE 611
            :.|  |.:|.::|.           ||.: .||||.                    .|..:::|.
Mosquito   418 IFR--DYKEGKILF-----------PPTY-KYNPGTDEWDSSEKSRTPAWCDRILWKGQRIEMLR 468

  Fly   612 SIVTTSYYLARFKDSYRQATIDLMLGNQ-----VSSESLSALGGQAGPDENDGTENAEQAKLLVE 671
            .........:..|..|....:|....:|     ||.|.|..:         |..||..|.::.||
Mosquito   469 YNSVMQLRKSDHKPVYADFKVDAQAKDQAKLKKVSEEVLKTV---------DKYENDNQPQITVE 524

  Fly   672 DCRRLLLGTAQYPVGAWGLIDADPSSGDINETEVDTILLLTDDCYIVAEY 721
            .                  .|.|......|| :....||:.::|::...:
Mosquito   525 Q------------------TDLDFGLIRFNE-KYSRELLVANNCHLPVRF 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sp3	NP_001036740.2	COG5329	<197..586	CDD:227637	87/473 (18%)
		hSac2	663..768	CDD:463592	10/59 (17%)
Ocrl	XP_558090.4	None