Protein Alignment sp3 and Ocrl

DIOPT Version :10

• Sequence 1: NP_001036740.2
• Gene: sp3 / 42545
• FlyBaseID: FBgn0038890
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: NP_569962.2
• Gene: Ocrl / 31157
• FlyBaseID: FBgn0023508
• Length: 850
• Species: Drosophila melanogaster
• Alignment Length: 570
• Identity: 118/570 - (20%)
• Similarity: 190/570 - (33%)
• Gaps: 189/570 - (33%)

  Fly   509 IISRQYAGTNALKG-DYTRTGERKISGMMKDGMNSANRFFI-------QNF---ADSFRQCIIDL 562
            ::|.|..||.|:.. .|.||           .::|||...|       .||   .||  :..|..
  Fly    55 LVSSQSGGTFAIIAFSYLRT-----------PLSSANELIINKVFAIDHNFQLRQDS--KSSITT 106

  Fly   563 MQGQLLRAED------------LQEDEVLSTILQILT------PETRPP---LHGYYNPGVLGPE 606
            .|..|..|||            ...:|.::.::...:      |||...   |:.|...|.:..|
  Fly   107 QQFDLSTAEDGPIKYYYYATESHHYEEFVAKVISFKSTMAQHDPETVLNFRWLNDYRQIGEVKQE 171

  Fly   607 LQLLESIVTTSYYLARFKDSYRQ-ATIDLMLGNQVSSESLSALGGQAGPDENDGTENAEQAKLLV 670
            |:..|     |.|:. :||.... ||.:  :.|:..|:|.:.|
  Fly   172 LKKRE-----SEYIV-YKDIIIYCATWN--VNNKTCSDSNNPL---------------------- 206

  Fly   671 EDCRRLLLGTAQYP--VGAWGLIDAD-PSSGDINETEVDTIL-----LLTDDCYIVAEYD---SH 724
                |..|..::.|  :.|.||.:.| |:...:|.|:|..|.     .:.|..:...||:   ||
  Fly   207 ----RAWLACSEKPPDIYAIGLQELDTPTKAMLNSTQVQAIEKQWIDKMMDSVHPDVEYEILMSH 267

  Fly   725 LDKIVRFEKVQLTQVRLIELGMH----QQTKIFQG-------SAPAHLCLRLNYSVDEQEGYFHM 778
                 |.....||.:...:|..|    :...:.:|       .....:.|:||      ||
  Fly   268 -----RLVATMLTVIVRKQLRQHIIRCRPKSVARGIFNTLGNKGGVAISLQLN------EG---- 317

  Fly   779 FRSANLRFFN-----NMAYVIKTQEEVAESMTSIVEMFRIALDNAGNT-----EVRYITGGVLQR 833
                |:.|.|     :|.||    ||..:...:|||..|.   :.|.|     .:.::  |.|..
  Fly   318 ----NICFVNSHLAAHMGYV----EERNQDYNAIVEGIRF---DDGRTISDHDHIFWV--GDLNY 369

  Fly   834 RKSKLPTLDVPRGM--PRNLSESQLVQLSSKALSNMAGQFSKLGQTFKKPQAHPSSLAATMNPQV 896
            |      :..|.|.  |..||::|..:|..        |:.:|.|..::.:.........:..:.
  Fly   370 R------IQEPPGQQRPGPLSDAQTYELLL--------QYDQLRQEMRRGKCFEGYTEGEIKFRP 420

  Fly   897 MRQRDSEIESGQEAEK--------AVFTLGRK----------------HRNSNSASSTDTDEHDN 937
            ..:.|...::...:||        .|...|.:                |:...:.........|.
  Fly   421 TYKYDPGTDNYDSSEKQRAPAYCDRVLWKGTRIEQLAYNSIMEIRQSDHKPVYAVFQVKVKTRDE 485

  Fly   938 SLYEPEVDSDVEIAMDKSNYNENAFLPSVG-----IVMGNQKEDSPSSSD 982
            ..|: .|..:|..|:||   .||...|.:.     |..|..:.:.||:.|
  Fly   486 VKYK-RVQEEVLKAVDK---RENDNQPQINVEKTVIDFGTVRFNEPSTRD 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sp3	NP_001036740.2	COG5329	<197..586	CDD:227637	23/99 (23%)
		hSac2	663..768	CDD:463592	26/126 (21%)
Ocrl	NP_569962.2	INPP5B_PH	23..160	CDD:465268	26/117 (22%)
		INPP5c_INPP5B	185..478	CDD:197327	67/362 (19%)
		RhoGAP_OCRL1	614..823	CDD:239845