Protein Alignment sp3 and Inpp5k

DIOPT Version :10

• Sequence 1: NP_001036740.2
• Gene: sp3 / 42545
• FlyBaseID: FBgn0038890
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: XP_006532570.1
• Gene: Inpp5k / 19062
• MGIID: 1194899
• Length: 472
• Species: Mus musculus
• Alignment Length: 470
• Identity: 89/470 - (18%)
• Similarity: 133/470 - (28%)
• Gaps: 209/470 - (44%)

  Fly   393 VIKLNNDRL---IYVTFDFHDYCRGMRFENVSALIDAVGPEAGAMGFHWRDQRGMICNQKSVFRV 454
            :::|||..|   ||:.     ..:.|.|..:|.|.||      |....|          .|:|
Mouse    53 LLQLNNQDLNLDIYII-----GLQEMNFGIISLLSDA------AFEDPW----------SSLF-- 94

  Fly   455 NCMDCLDRTNVVQTAIGKAVLESQLVKLGL---------SPPYTPIPEQLKSP--FMVLWANNGD 508
              ||.|...|.|:.        ||:...||         ..||..|.....:|  ....|.|.|
Mouse    95 --MDMLSPLNFVKI--------SQVRMQGLLLLVFAKYQHLPYIQIISTKSTPTGLYGYWGNKG- 148

  Fly   509 IISRQYAGTNA---LKGDYT------------------RTGERKISGMMKDGMNSAN-------- 544
                   |.|.   |.|.|.                  ...:|.:..:..:|.:..|
Mouse   149 -------GVNVCLKLYGYYVSIINCHLPPHMYNNDQRLEHFDRILESLTFEGYDVPNILDHDLIL 206

  Fly   545 -----RFFIQNFADSF----------------RQCIIDLMQGQLLRAEDLQEDEVLSTILQILTP 588
                 .|.|::|...|                .|..|.....||||  :.||..:|.
Mouse   207 WFGDMNFRIEDFGLLFVQESITRKYYKELWEKDQLFIAKKNDQLLR--EFQEGPLLF-------- 261

  Fly   589 ETRPPLHGY------YN---------------------PGVLGPELQLLESIVTTSYYLARFKD- 625
               ||.:.:      |:                     |....|    |.|.|.|||:|...|:
Mouse   262 ---PPTYKFDRHSNNYDTSEKKRKPAWTDRILWRLKRQPSQASP----LASSVPTSYFLLTLKNY 319

  Fly   626 ----SYR-------QATIDLMLGNQVSSESLSALGGQAGPDENDGTENAEQAKLLVEDCRRLLLG 679
                :|.       ..|.||.|...:|...::.:.......|||         :|:.     ...
Mouse   320 VSHMAYSISDHKPVTGTFDLELNPLMSVPLITMMPEHLWTMEND---------MLIS-----YTS 370

  Fly   680 TAQYPVGAWGLI------------------------DADPSSGD------INETEVDTILLLTDD 714
            |.::...:|..|                        |...|.|:      ||.:.:..    |:|
Mouse   371 TPEFLSSSWDWIGLYKVIQQVGMRHINDYVAYVWVGDNQVSYGNNPNQVYINISAIPD----TED 431

  Fly   715 CYIVAEYDSHLDKIV 729
            .:::..|.::|..:|
Mouse   432 QFLLCYYSNNLHSVV 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sp3	NP_001036740.2	COG5329	<197..586	CDD:227637	53/256 (21%)
		hSac2	663..768	CDD:463592	14/97 (14%)
Inpp5k	XP_006532570.1	EEP	32..339	CDD:469791	68/343 (20%)
		SKICH	350..454	CDD:465482	17/115 (15%)