Protein Alignment sp3 and figo-1

DIOPT Version :10

• Sequence 1: NP_001036740.2
• Gene: sp3 / 42545
• FlyBaseID: FBgn0038890
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: NP_492266.2
• Gene: figo-1 / 172620
• WormBaseID: WBGene00007912
• Length: 905
• Species: Caenorhabditis elegans
• Alignment Length: 946
• Identity: 209/946 - (22%)
• Similarity: 345/946 - (36%)
• Gaps: 310/946 - (32%)

  Fly    22 HRRTSEFSIKAGWDLSSVDDIECIGVTHGIVGVISLPNVYEPHLVVVKEASAVGVL-YPPHLVYK 85
            :|.:|:...|:|.       ||......||:|.:.....|  :|:::..|.||..| |  |.|||
 Worm    71 YRSSSKKGTKSGL-------IERATNAFGILGCVRFVEGY--YLIIITRAHAVATLGY--HPVYK 124

  Fly    86 IKSICILS-ADDPDTDLPNCTKHTKSNQSTPTHSVSTSNNNNASVPSSGGGSSKSTKLFEGMNKT 149
            |..:.::. |.|                     .||||:.           ..|..|||
 Worm   125 IVEVAMIPIAMD---------------------GVSTSSE-----------EQKYVKLF------ 151

  Fly   150 WGAVKSAGNTIKNTTQQAANLATKQVKSSVGIREPRHIERRITEELHKIFDETDSFYFSFDCDIT 214
                            |:.:|:|                               .||||:..|::
 Worm   152 ----------------QSVDLST-------------------------------DFYFSYSYDMS 169

  Fly   215 NNLQRHEAKSE-----ESQSQPDERFFWNKHMIRDL-INLNDKTWILPIIQGFMQVENCVIGNEC 273
            ...|.:..:|:     :.:.:.||||.||..::..| .||..:.|.:.|:.|:::.|...:....
 Worm   170 RTFQENSLRSDWNNHGQRRLEADERFVWNSFLLEPLRKNLISERWFVEIVHGYVRQEYIFLPIGR 234

  Fly   274 FTLALVSRRSRHRAGTRYKRRGVDEKGNCANYVETEQIL------------SFRHHQLSFTQVRG 326
            .:|.::.|||...||||:.:||.:..||.|||||||||:            .|.    ||.|:||
 Worm   235 ISLTIIGRRSTKYAGTRFLKRGANPTGNVANYVETEQIVWDMASSGNVADGRFS----SFVQMRG 295

  Fly   327 SVPIYWSQP----GYKYRPPPRLDRGVAETQQAFELHFTKELETYGR-VCIVNLVEQSGKEKTIG 386
            |||:.|||.    |...:|...:|......|.|.. ||......||. :.|:||::::.|.:..|
 Worm   296 SVPMRWSQDPSTRGVVGKPLILIDNHEPHAQTAAS-HFRDVRNKYGNPIVIMNLIKRNEKRRHEG 359

  Fly   387 DAYADHVIKL--------NNDRLIYVTFDF---HDYCRGMRFENVSALIDAVG------------ 428
            ..:...:..:        |.::|.|::||.   :.....|...||..:::.:.
 Worm   360 VLHTQFLKNIEYLNQFLPNEEKLCYISFDVARCNKAANSMPSINVLNVMEDLSMKSILKNGWFQS 424

  Fly   429 -PEAGAM------------GFHWRDQRGMICNQKSVFRVNCMDCLDRTNVVQTAIGKAVLESQLV 480
             |.:.|:            ..|.:|.|.||  |..:.|.||:||||||||.|..|.|..|..||.
 Worm   425 FPLSEALKIRPREAFATLDAHHSKDGRFMI--QHGICRTNCVDCLDRTNVAQFVIAKVALGCQLC 487

  Fly   481 KLG-LSPPYTPIPEQLKSPFMVLWANNGDIISRQYAGTNALKG--DYTRTG---ERKISGMMKDG 539
            .:| |..|...:..::......::..:||.::.||||:..:..  .|.:|.   ||:     :|.
 Worm   488 AMGILDEPNLTLQSEVCRLLEDMFDEHGDTMALQYAGSQLVHSIKTYKKTAAFQERR-----RDV 547

  Fly   540 MNSANRFFIQNFADSFRQCIIDLMQGQLLRAEDLQEDEVLSTILQILTPETRPPLHGYYNPGVLG 604
            ..:.:|::...|.|..:|..|:|..                                    ||..
 Worm   548 FQTLSRYYSNTFNDWDKQMAINLFL------------------------------------GVFR 576

  Fly   605 PELQLLESI--VTTSY-----YLARFKDSYRQATIDLMLGNQVSSESLSALGGQAGPDENDGTEN 662
            |.:..::::  :|:.|     |..:....|...|:     ::...|.|..|    ..||::.::.
 Worm   577 PRITTMKNLWDLTSDYNLHFPYSLKINTDYCAWTL-----SEKELEDLVFL----DYDESENSDG 632

  Fly   663 AEQAKLLVEDCRRLLLGTAQYPVGAWGLIDADPSSGDINETEVDTILLLTD----DCYIVAEYDS 723
            ..:.:.:..|.||          |:.|             :|..|:|..:.    |.:...|:.|
 Worm   633 YVEIRSIDVDGRR----------GSEG-------------SEYRTLLFSSHEDFRDYHRTYEFTS 674

  Fly   724 HLDKIVRFEKVQ-------------LTQVRLIELGMHQQTKIFQGSAPAHLCLRLNYSVDEQEGY 775
            ..|:|.|...::             .|..:.::|....:||......|.........|.||.:
 Worm   675 LDDRIGRLFSIENRAIQVDGINEEPTTHAQFLKLWKTTETKEKDQKKPNKKDKEEKESDDEDD-- 737

  Fly   776 FHMFRSANLRFFNNMAYVIKTQEEVAESMTSIVEMFRIALD--NA-GNTEVRYITGGVLQRRKSK 837
                                 .||::...:.:||..:...|  || ||...      .||:..:|
 Worm   738 ---------------------DEEISTQWSDVVEAQQEWYDLVNAPGNVTT------TLQKSPTK 775

  Fly   838 LPTLDVPRGMPRNLSESQLVQLSSKALSNMAGQFSK 873
            ..:..     |||.|.::      ::|.:...||:|
 Worm   776 RESTP-----PRNTSRAK------RSLLSTGLQFAK 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sp3	NP_001036740.2	COG5329	<197..586	CDD:227637	120/453 (26%)
		hSac2	663..768	CDD:463592	19/121 (16%)
figo-1	NP_492266.2	Syja_N	91..394	CDD:460545	100/396 (25%)