Protein Alignment sp3 and Inpp5d

DIOPT Version :10

• Sequence 1: NP_001036740.2
• Gene: sp3 / 42545
• FlyBaseID: FBgn0038890
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: XP_006529212.1
• Gene: Inpp5d / 16331
• MGIID: 107357
• Length: 1196
• Species: Mus musculus
• Alignment Length: 279
• Identity: 60/279 - (21%)
• Similarity: 107/279 - (38%)
• Gaps: 92/279 - (32%)

  Fly   934 EHDNSLYEPEVDSDVEIAMDKSNYNENAFLPSVGIVMG---NQKEDSPSSSD-----EIRHLEQK 990
            |.::::.|.|.|: ||..|....      ||...|.|.   ::.:|.|.:::     |:..|...
Mouse   107 EEEDAIDEAEEDT-VESVMSPPE------LPPRNIPMSAGPSEAKDLPLATENPRAPEVTRLSLS 164

  Fly   991 DSM----------------CKTTEDVLTISITSVTDHVGLPTGLLENAPAIRPITPNPLICVEAH 1039
            :::                .|..:|.|:..:...:|.  |.|| ..|.|.::.:.  .|:|.|.|
Mouse   165 ETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLLLDSDF--LKTG-SSNLPHLKKLM--SLLCKELH 224

  Fly  1040 EAFDDREEGVKPVSSTSA------RDLSLPGLPTHP----EAN------KLKQLTSPLSKL---- 1084
                  .|.::.:.|..:      :.|| |||...|    ||:      ||.||||.||.:
Mouse   225 ------GEVIRTLPSLESLQRLFDQQLS-PGLRPRPQVPGEASPITMVAKLSQLTSLLSSIEDKV 282

  Fly  1085 -------------------------AKNIGLNLDPRKIATKTGVLSPTILSAENSPPERDP-SSR 1123
                                     ::::|:   |:|:..|..|.|..::..::.....|. .|.
Mouse   283 KSLLHEGSESTNRRSLIPPVTFEVKSESLGI---PQKMHLKVDVESGKLIVKKSKDGSEDKFYSH 344

  Fly  1124 DHLLELWEAEKCKTKLIAL 1142
            ..:|:|.:::|...||:.|
Mouse   345 KKILQLIKSQKFLNKLVIL 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sp3	NP_001036740.2	COG5329	<197..586	CDD:227637
		hSac2	663..768	CDD:463592
Inpp5d	XP_006529212.1	SH2_SHIP	4..105	CDD:198206
		INPP5c_SHIP1-INPP5D	407..713	CDD:197334