DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7956 and sacm1l

DIOPT Version :9

Sequence 1:	NP_001036740.2	Gene:	CG7956 / 42545	FlyBaseID:	FBgn0038890	Length:	1142	Species:	Drosophila melanogaster
Sequence 2:	NP_001344516.1	Gene:	sacm1l / 100497354	XenbaseID:	XB-GENE-920710	Length:	608	Species:	Xenopus tropicalis

Alignment Length:	573	Identity:	187/573 - (32%)
Similarity:	274/573 - (47%)	Gaps:	113/573 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LSSVDDIECIGVT---HGIVGVISLPNVYEPHLVVVKEASAVGVLYPPHLVYKIKSICILSADDP 97
            |:...||....:|   :||:|.|.|  |...:|:|:.....||.|. .|.::|.....|:
Frog    41 LTGKKDIPPSAITRAIYGILGTIRL--VAGMYLIVITRKKKVGDLL-NHSIWKATDFDII----- 97

  Fly    98 DTDLPNCTKHTKSNQSTPTHSVSTSNNNNASVPSSGGGSSKSTKLFEGMNKTWGAVKSAGNTIKN 162
                        |.:.|..|...|...:|              |.|..|
Frog    98 ------------SYKKTMLHLTDTQLQDN--------------KAFLAM---------------- 120

  Fly   163 TTQQAANLATKQVKSSVGIREPRHIERRITEELHKIFDETDSFYFSFDCDITNNLQRHEAKSEES 227
                                        |:..|     ..|.||||...|:|:.|||....|.|.
Frog   121 ----------------------------ISHVL-----SVDGFYFSVSYDLTHTLQRLSNTSPEF 152

  Fly   228 Q-----SQPDERFFWNKHMIRDLINLND-KTWILPIIQGFMQVENCVIGNECFTLALVSRRSRHR 286
            |     .:.|:||.||.|::|:.....: :.:.:|::.||:.:.:|.|..:.|...|:||||..|
Frog   153 QEMSLLERADQRFVWNGHLLREFSAQPEIQKFAIPVVHGFIAIHSCSINGKYFDWILISRRSCFR 217

  Fly   287 AGTRYKRRGVDEKGNCANYVETEQILSFRHHQLSFTQVRGSVPIYWSQ-PGYKYRPPPRLDRGVA 350
            ||.||..||:|.:|:.||:||||||:.:..::.||.|.|||:|.|||| |..||:|.|::.:.|
Frog   218 AGVRYYVRGIDSEGHAANFVETEQIVHYNGNKASFVQTRGSIPFYWSQRPNLKYKPKPQISKAV- 281

  Fly   351 ETQQAFELHFTKELETYGRVCIVNLVEQSGKEKTIGDAYADHVIKLNNDRLIYVTFDFHDYCRGM 415
            .....|:.||..::.:||:..::|||.|.|.||.:..|::..|..|.|..|.|:.||||..|..|
Frog   282 NHMDGFQRHFDSQIISYGKQVVLNLVNQKGSEKPLEQAFSQMVSGLGNGMLRYIAFDFHKECSRM 346

  Fly   416 RFENVSALIDAVGPEAGAMGFHWRDQRG-MICNQKSVFRVNCMDCLDRTNVVQTAIGKAVLESQL 479
            |::.:..|:|.|.......|:...|..| ::..|:.:||.|||||||||||||:.:.:..|:.||
Frog   347 RWDRLQILVDQVSETQDDFGYFLVDSDGKVVSQQEGIFRSNCMDCLDRTNVVQSLLARRSLQFQL 411

  Fly   480 VKLGLSPPYTPIPEQL--KSPFMVLWANNGDIISRQYAGTNALKGDYTRTGERKISGMMKDGMNS 542
            .:||:......|.||:  :..:...||:|.:..::|||||.|||.|:||||:|...|::.||.||
Frog   412 QRLGVLHVGQRIEEQIQFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTQWGLLMDGWNS 476

  Fly   543 ANRFFIQNFADSFRQCIIDLMQGQLLRAEDLQEDEVLSTILQILTPETRPPLH 595
            ..|::..||:|.|||..|||..|      :...:||.|:          .|||
Frog   477 LMRYYKNNFSDGFRQDSIDLFLG------NYSVEEVYSS----------SPLH 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7956	NP_001036740.2	Syja_N	174..413	CDD:280532	89/245 (36%)
		COG5329	<197..586	CDD:227637	156/398 (39%)
		hSac2	663..768	CDD:289241
sacm1l	NP_001344516.1	COG5329	33..518	CDD:227637	187/573 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D153624at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010