Protein Alignment sp3 and inpp5jb

DIOPT Version :10

• Sequence 1: NP_001036740.2
• Gene: sp3 / 42545
• FlyBaseID: FBgn0038890
• Length: 1142
• Species: Drosophila melanogaster
• Sequence 2: XP_002662241.3
• Gene: inpp5jb / 100317089
• ZFINID: ZDB-GENE-081104-46
• Length: 657
• Species: Danio rerio
• Alignment Length: 565
• Identity: 105/565 - (18%)
• Similarity: 188/565 - (33%)
• Gaps: 169/565 - (29%)

  Fly   552 ADSFRQCIIDLMQGQLLRAEDLQEDEVLSTILQILTPETRPPLHGYYNPGVLGPELQLLESIVTT 616
            |:.||..|:....|..:..||      ::.:|.:...:....::      ::|  ||.:.|::..
Zfish   143 AEDFRIHIVTWNVGSAMPPED------ITNLLGLNVGDGNTDMY------IIG--LQEVNSMINK 193

  Fly   617 SYYLARFKDSYRQATIDLMLGNQVSSESLSALGGQAGPDENDGTENAEQAKLLV----------- 670
            ......|.|.:          ::|..::||..|...      .|....|..||:
Zfish   194 RLKDVLFTDQW----------SEVCMDALSPFGYVL------ATSQRMQGMLLLVFAKYFHLPFL 242

  Fly   671 ----EDCRRLLLGTAQYPVGAWGLIDADPSSGDINETEV---DTILLLTDDCYIVAEYDSHLDKI 728
                ....|..||      |.||      :.|.::....   .:|..|  :|::.|..::...::
Zfish   243 RGIQTQTTRTGLG------GIWG------NKGGVSARMTVFGHSICFL--NCHLPAHMENTEQRM 293

  Fly   729 VRFEKVQLTQVRLIELGMHQQTKIFQGSAPAHLCLR--------LNYSVDEQEGYFHMFRSANLR 785
            ..||.:           :.||.  |.|.|...:...        ||:.:::.|  ..:.:.|
Zfish   294 EDFESI-----------LQQQQ--FDGQAATGVLDHDVVFWFGDLNFRIEDLE--MQVVKGA--- 340

  Fly   786 FFNNMAYVI--KTQEEVAESMTSIVEMFR---------IALDNAGNTEVRYITGGVLQRRKSKLP 839
            ..||...|:  |.|..:|:...:::|.|.         ...|...:|   |.|.|     |.::|
Zfish   341 IDNNKLSVLWEKDQLNIAKDSETVLEGFHEGPLKFPPTYKFDVGTDT---YDTSG-----KKRMP 397

  Fly   840 TLDVPRGMPRNLSESQLVQLSSKALSNMAGQFS--KLGQTFKKPQAH-------PSSLAATMN-- 893
            .. ..|.:.|....:|:...:||. |:::|..|  ::.|.|.:....       |.|...|:.
Zfish   398 AW-TDRILWRLRPMAQVSNSTSKR-SSLSGLTSGTRVSQHFYRSHMEYTVSDHKPVSSVFTLQFP 460

  Fly   894 -----PQV-------MRQRDSEIESGQEAEK---------AVFTLGRKHRNSNSASSTDTDEHDN 937
                 |.|       .|:....:...:.|..         .::.:|.||.....|.:....|..:
Zfish   461 YKVDMPLVTIFVEDEWREISDAVAKFKVAPNFARSSWDWIGIYKVGFKHHKDYVAYTWAKQEESD 525

  Fly   938 SLYEPEVDSDVEIAMDKSN------YNENAFLPSVGI------------VMGNQKEDSP--SSSD 982
            .|.:....:..|..:.|.:      |..|.....|||            ..|....||.  :|.|
Zfish   526 FLRQEHQVNFTEEELPKESGDFILGYYSNNTSSIVGITEPFQIQLPASAAAGLSPSDSSDFTSDD 590

  Fly   983 EIRHLEQKDSMCKTTEDVLTISITSVTDHVGLPTGLLENAPAIRP 1027
            |::..:..|| ...|||.::..:|.  :.:..|     :.|..||
Zfish   591 EVKKPDSGDS-SPETEDPVSSRLTE--EQMAKP-----SRPHARP 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sp3	NP_001036740.2	COG5329	<197..586	CDD:227637	8/33 (24%)
		hSac2	663..768	CDD:463592	23/130 (18%)
inpp5jb	XP_002662241.3	INPP5c_INPP5J-like	146..457	CDD:197328	70/382 (18%)
		SKICH	468..568	CDD:465482	16/99 (16%)