Protein Alignment C15 and BARX2

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_003649.2
• Gene: BARX2 / 8538
• HGNCID: 956
• Length: 279
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 72/221 - (32%)
• Similarity: 98/221 - (44%)
• Gaps: 28/221 - (12%)

  Fly   102 SSPGSSSNNNNSGEKGEEKELLQQEDHDLAYKLATSIANSTYGSAAALYSYPHLYPSAAGGHVLR 166
            ||||.........:.....|:|.:|..|...||      |.|....:|...|....|..|...||
Human    10 SSPGQLKAARRRYKTFMIDEILSKETCDYFEKL------SLYSVCPSLVVRPKPLHSCTGSPSLR 68

  Fly   167 VPP-----QRTP-----LTWALPPLHHAALAHQAVKDRLAAAFPIARRI--GHPYQNRTPPKRKK 219
            ..|     .|.|     |..|.|.:..|...|| |.:.::|..|....:  ......:..|::||
Human    69 AYPLLSVITRQPTVISHLVPATPGIAQALSCHQ-VTEAVSAEAPGGEALASSESETEQPTPRQKK 132

  Fly   220 P---RTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRR------Q 275
            |   ||.||.:|:..|||:|.|||||::.:|..||:.|.:|..|||||:||||.||::      |
Human   133 PRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTWYQNRRMKWKKMVLKGGQ 197

  Fly   276 TAEEREAERQAANRLMLSLQAEAISK 301
            .|..:...|...|.:..|.:.||..|
Human   198 EAPTKPKGRPKKNSIPTSEEIEAEEK 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	44/117 (38%)
		Homeodomain	218..274	CDD:459649	33/58 (57%)
BARX2	NP_003649.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..137		5/26 (19%)
		Homeodomain	134..190	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..279		8/30 (27%)