DRSC/TRiP Functional Genomics Resources

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Protein Alignment C15 and Tlx3

DIOPT Version :9

Sequence 1:NP_476873.2 Gene:C15 / 42544 FlyBaseID:FBgn0004863 Length:339 Species:Drosophila melanogaster
Sequence 2:XP_573065.4 Gene:Tlx3 / 497881 RGDID:1564190 Length:291 Species:Rattus norvegicus


Alignment Length:271 Identity:127/271 - (46%)
Similarity:147/271 - (54%) Gaps:68/271 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   121 ELLQQEDHDLAYKLATSIANSTYGSAAALY-----------SYPHLYPSAAG------------- 161
            ::|...|.|        .|.:..|...|.|           :||.|..|.||             
  Rat    22 QILNSPDQD--------SAPAPRGPDGASYLGGPPGGRPGAAYPSLPASFAGLGAPFEDAGSYSV 78

  Fly   162 ------GHVLRVPPQRTPLTWALPPLHHAAL----------------------AHQAVKDRLAAA 198
                  ..|:|||..| ||..|:||...:||                      :.:.||||..||
  Rat    79 NLSLAPAGVIRVPAHR-PLPGAVPPPLPSALPAMPSVPTVSSLGGLNFPWMESSRRFVKDRFTAA 142

  Fly   199 -----FPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTD 258
                 |.:.||||||||||||||||||||||:|:|:.|||||||:|||||||||||||:.|||||
  Rat   143 AALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTD 207

  Fly   259 AQVKTWFQNRRTKWRRQTAEEREAERQAANRLMLSLQAEAISKGFAPPSAPLGSQGGVNGAPLAA 323
            |||||||||||||||||||||||||||.|:||||.||.:|..|.......|  ....::.:.|.|
  Rat   208 AQVKTWFQNRRTKWRRQTAEEREAERQQASRLMLQLQHDAFQKSLNDSIQP--DPLCLHNSSLFA 270

  Fly   324 LHGLQPWAEAS 334
            |..||||.|.|
  Rat   271 LQNLQPWEEDS 281

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
C15NP_476873.2 COG5576 <196..315 CDD:227863 89/123 (72%)
Homeobox 220..273 CDD:278475 45/52 (87%)
Tlx3XP_573065.4 Homeobox 169..223 CDD:395001 46/53 (87%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 111 1.000 Domainoid score I6110
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 200 1.000 Inparanoid score I3708
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1391465at2759
OrthoFinder 1 1.000 - - FOG0001097
OrthoInspector 1 1.000 - - otm44573
orthoMCL 1 0.900 - - OOG6_107582
Panther 1 1.100 - - LDO PTHR45921
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X1533
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
109.970

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