Protein Alignment C15 and Nkx2-4

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: XP_038962557.1
• Gene: Nkx2-4 / 366213
• RGDID: 1304985
• Length: 353
• Species: Rattus norvegicus
• Alignment Length: 326
• Identity: 80/326 - (24%)
• Similarity: 124/326 - (38%)
• Gaps: 88/326 - (26%)

  Fly    69 SSSENLPFSISRLLSKPFETSHHHHNNNNHLLSSSP--------GSSSNNNNSGEKGEEKELL-Q 124
            |.....|||:|.:|| |.|.::.....   ::..:|        .::.....:|...:...:. .
  Rat     4 SPKHTTPFSVSDILS-PIEETYKKFGG---VMDGAPPGLGAPLGAAAYRAPPTGPSSQAAAVAGM 64

  Fly   125 QEDHDLAYKLATSIANSTYGSAAALYSYPHLYP-------------------------------- 157
            |..|.:|...|.:.|.:...:|||..:| |:.|
  Rat    65 QPPHAMAGHNAAAAAAAAAAAAAAAATY-HMPPGVSQFPHSAMGSYCNGGLGNMGELPAYTDGMR 128

  Fly   158 -----SAAGGHVLRVPPQRTPLTWALPPLHHAALAHQAVKDRLAAAFPIARRIGHPYQNRTPPKR 217
                 :|.|.:.....|:.:.::..:.|   :|..:.|....|......|:.:. |.....|  |
  Rat   129 GGAAAAATGWYGANTDPRYSSISRFMGP---SAGVNVAGMGSLTGIADAAKSLA-PLHAAAP--R 187

  Fly   218 KKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREA 282
            :|.|..|::.||.|||:||.:||||::.||..||..:.:|..|||.||||.|.|.:|| |:::.|
  Rat   188 RKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQ-AKDKAA 251

  Fly   283 ERQAANRLMLSLQAEAISKGFAPPSAP-----------------LGSQGGVNGAPLAALHGLQPW 330
            ::         ||.|.   |..||..|                 ...|.|. |.|.....|.||.
  Rat   252 QQ---------LQQEG---GLGPPPPPPPPSPRRVAVPVLVKDGKPCQNGA-GTPTPGQGGQQPQ 303

  Fly   331 A 331
            |
  Rat   304 A 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	44/135 (33%)
		Homeodomain	218..274	CDD:459649	28/55 (51%)
Nkx2-4	XP_038962557.1	Homeodomain	188..244	CDD:459649	28/55 (51%)