Protein Alignment C15 and en

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 443
• Identity: 95/443 - (21%)
• Similarity: 147/443 - (33%)
• Gaps: 182/443 - (41%)

  Fly     1 MSSHEEDDHEHENEHGEEVEEQEIHVDVDSDSRMSCGSGSDVDMDGGSCYDESETPLSESLQSEQ 65
            ||.|.:....:|.|..|  |:.:|.||||..|.            ||..     .|     .:.|
  Fly   124 MSFHNQTHTTNEEEEAE--EDDDIDVDVDDTSA------------GGRL-----PP-----PAHQ 164

  Fly    66 TRSSSSENLPFSISRLLS--------------------KPFETSH-------------------- 90
            .:|::..:|.||||.:||                    :|||.|.
  Fly   165 QQSTAKPSLAFSISNILSDRFGDVQKPGKSMENQASIFRPFEASRSQTATPSAFTRVDLLEFSRQ 229

  Fly    91 -------------------------------HHHNNNNHLLSSS-------PGSSSNNNNSGEKG 117
                                           |.....:.|..|:       |.||..::.:.||.
  Fly   230 QQAAAAAATAAMMLERANFLNCFNPAAYPRIHEEIVQSRLRRSAANAVIPPPMSSKMSDANPEKS 294

  Fly   118 EEKEL-------------------LQQEDHDLA--------------YKLATSIANSTYG---SA 146
            ....|                   |......||              ..:|||.::|:.|   :|
  Fly   295 ALGSLCKAVSQIGQPAAPTMTQPPLSSSASSLASPPPASNASTISSTSSVATSSSSSSSGCSSAA 359

  Fly   147 AALYSYPHLYPSAAGGHVLRVPPQRTPLTWALPPLHHAALAH-------------------QAVK 192
            ::|.|.|.....|:|..|....||..|:.   ||   :|::.                   :..|
  Fly   360 SSLNSSPSSRLGASGSGVNASSPQPQPIP---PP---SAVSRDSGMESSDDTRSETGSTTTEGGK 418

  Fly   193 DRLAAAFPIARRI------GHPYQNRTPPK-----RKKPRTSFTRIQVAELEKRFHKQKYLASAE 246
            :.:..|:....|.      |..|:....||     .|:|||:|:..|:|.|::.|::.:||....
  Fly   419 NEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDKTNDEKRPRTAFSSEQLARLKREFNENRYLTERR 483

  Fly   247 RAALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQAANRLMLSLQAEAI 299
            |..|:..|.:.:||:|.||||:|.|.::.|..:        |.|.|.|.|:.:
  Fly   484 RQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSK--------NPLALQLMAQGL 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	35/115 (30%)
		Homeodomain	218..274	CDD:459649	23/55 (42%)
en	NP_523700.2	Homeodomain	455..511	CDD:459649	23/55 (42%)
		Engrail_1_C_sig	512..542	CDD:431338	6/25 (24%)