Protein Alignment C15 and HOXD10

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_002139.2
• Gene: HOXD10 / 3236
• HGNCID: 5133
• Length: 340
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 72/299 - (24%)
• Similarity: 112/299 - (37%)
• Gaps: 50/299 - (16%)

  Fly    11 HENEHGEEVEEQEIHVDVDSDSRMSCGSGSDVDMDGGSCYDESETPLSES----LQSEQTRSSSS 71
            |:| .|..|......||..:|...||.....|.....:|  ...|.:.|.    :.|::.....|
Human    64 HQN-MGMNVHPYIPQVDSWTDPNRSCRIEQPVTQQVPTC--SFTTNIKEESNCCMYSDKRNKLIS 125

  Fly    72 ENLPFSISRL-------------------LSKPFETSHHHHNNNNHLLSSSPGSSSNNNNSGEKG 117
            ..:| |..||                   ||:.:.|......||     |..|||:.......:|
Human   126 AEVP-SYQRLVPESCPVENPEVPVPGYFRLSQTYATGKTQEYNN-----SPEGSSTVMLQLNPRG 184

  Fly   118 EEKELLQQEDHDLAYKLATSIANSTYGSAAALYSYPHLYPSAAGGHVLRVPPQRTPLTWALPPLH 182
            ..|..|......:..|:...::.......:.:.|     |.|.||    :|.:|:.|  |...:.
Human   185 AAKPQLSAAQLQMEKKMNEPVSGQEPTKVSQVES-----PEAKGG----LPEERSCL--AEVSVS 238

  Fly   183 HAALAHQAVKDRLAAAFPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAER 247
            ...:..:..|:.:.:..|.:..:       |....:|.|..:|:.|..||||.|....||....|
Human   239 SPEVQEKESKEEIKSDTPTSNWL-------TAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERR 296

  Fly   248 AALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQA 286
            ..:::.:.:||.|||.||||||.|.::.:.|.|..|..|
Human   297 LEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTA 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	30/91 (33%)
		Homeodomain	218..274	CDD:459649	24/55 (44%)
HOXD10	NP_002139.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..268		13/85 (15%)
		Homeodomain	267..323	CDD:459649	24/55 (44%)