Protein Alignment C15 and HOXD1

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_078777.1
• Gene: HOXD1 / 3231
• HGNCID: 5132
• Length: 328
• Species: Homo sapiens
• Alignment Length: 247
• Identity: 65/247 - (26%)
• Similarity: 84/247 - (34%)
• Gaps: 87/247 - (35%)

  Fly   135 ATSIANSTYG--SAAALYSYPHLYPSAA---GGHVLRVPPQRTPLTWALPPLHHAA--------- 185
            |.:...:.||  .:...|.:|.:...||   |.||                 |:|.
Human    98 AAAAGGADYGFLGSGPAYDFPGVLGRAADDGGSHV-----------------HYATSAVFSGGGS 145

  Fly   186 --LAHQAVKDRLA----AAFPI---ARRIGHP--YQNRTP-----PKRKKP-------------- 220
              |:.|.  |..|    ..||.   |...|||  :|..:|     ||...|
Human   146 FLLSGQV--DYAAFGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSVSPASGLPAAFSTFEWM 208

  Fly   221 ------------------------RTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQV 261
                                    ||:|:..|:.||||.||..|||..|.|..:|..|.:.|.||
Human   209 KVKRNASKKGKLAEYGAASPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQV 273

  Fly   262 KTWFQNRRTKWRRQTAEEREAERQAANRLMLSLQAEAISKGFAPPSAPLGSQ 313
            |.||||||.|.:::..|...|.......|.|.|.....:|....|.:|..||
Human   274 KIWFQNRRMKQKKREREGLLATAIPVAPLQLPLSGTTPTKFIKNPGSPSQSQ 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	50/170 (29%)
		Homeodomain	218..274	CDD:459649	29/93 (31%)
HOXD1	NP_078777.1	Antp-type hexapeptide	204..209		0/4 (0%)
		Homeodomain	233..286	CDD:459649	28/52 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..328		6/21 (29%)