Protein Alignment C15 and HOXC11

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_055027.1
• Gene: HOXC11 / 3227
• HGNCID: 5123
• Length: 304
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 57/228 - (25%)
• Similarity: 86/228 - (37%)
• Gaps: 73/228 - (32%)

  Fly    75 PFSISRLLSKPFETSH--HHHNNNNHLLSSSPGSSSNNNN------------------------- 112
            |.:::.:|.|. |.|:  |||.:..|...:...||.|.|:
Human   107 PSTVTEILMKN-EGSYGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPAEPP 170

  Fly   113 -SGEKGEEKELLQQEDHDLAYKLATSIANSTYGSAAALYSYPHLYPSAAGGHVLRVPPQRTPLTW 176
             || |||.|...:...       |:.:|:.....|.|.....:..||::|.
Human   171 CSG-KGEAKGEPEAPP-------ASGLASRAEAGAEAEAEEENTNPSSSGS-------------- 213

  Fly   177 ALPPLHHAALAHQAVKDRLAAAFPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKY 241
                      ||...|:....|.|.|            |:.:|.|..:::.|:.|||:.|....|
Human   214 ----------AHSVAKEPAKGAAPNA------------PRTRKKRCPYSKFQIRELEREFFFNVY 256

  Fly   242 LASAERAALARGLKMTDAQVKTWFQNRRTKWRR 274
            :...:|..|:|.|.:||.|||.||||||.|.::
Human   257 INKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	28/79 (35%)
		Homeodomain	218..274	CDD:459649	24/55 (44%)
HOXC11	NP_055027.1	DUF3528	42..161	CDD:432284	13/54 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..237		21/114 (18%)
		Homeodomain	233..289	CDD:459649	24/55 (44%)