Protein Alignment C15 and HOXC8

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_073149.1
• Gene: HOXC8 / 3224
• HGNCID: 5129
• Length: 242
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 57/242 - (23%)
• Similarity: 85/242 - (35%)
• Gaps: 84/242 - (34%)

  Fly    97 NHLLSSSPGSSSNNNNSGEKGEEKELLQQEDH---DLAYKLATSIANSTY----------GSAAA 148
            :|.|...||.|:..            .|...|   |..:...:.|:||.|          |.|:.
Human    35 SHALVYGPGGSAPG------------FQHASHHVQDFFHHGTSGISNSGYQQNPCSLSCHGDASK 87

  Fly   149 LYSY-----PHLYPSAAGGHVLRVPPQRTPLTWALPPLHHAALAHQAVKDRLAAAFPIARRIGHP 208
            .|.|     ..||.:.....|::.|..::                       :|....:...||.
Human    88 FYGYEALPRQSLYGAQQEASVVQYPDCKS-----------------------SANTNSSEGQGHL 129

  Fly   209 YQNRTP-----------PKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVK 262
            .||.:|           |.|:..|.:::|.|..||||.|....||....|..::..|.:|:.|||
Human   130 NQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVK 194

  Fly   263 TWFQNRRTKWRRQT--------------------AEEREAERQAANR 289
            .||||||.||:::.                    .||:|.|.:..|:
Human   195 IWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEEKEEEEKEENK 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	37/125 (30%)
		Homeodomain	218..274	CDD:459649	24/55 (44%)
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..154		8/62 (13%)
		Antp-type hexapeptide	138..143		0/4 (0%)
		Homeodomain	150..206	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..242		5/36 (14%)