Protein Alignment C15 and HOXC5

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_061826.1
• Gene: HOXC5 / 3222
• HGNCID: 5127
• Length: 222
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 58/211 - (27%)
• Similarity: 83/211 - (39%)
• Gaps: 66/211 - (31%)

  Fly   131 AYKLATSIANSTYGSA----AALYSY--------------------------PHLYP-------S 158
            ||.:.|.   ..||||    |:.|.|                          |..:|       :
Human    18 AYNMQTC---GNYGSASEVQASRYCYGGLDLSITFPPPAPSNSLHGVDMAANPRAHPDRPACSAA 79

  Fly   159 AAGGHVLRVPPQRTPLTWALPPLHHAALAHQAVKDRLAAAFPIAR---RIGHP---YQNRTPPK- 216
            ||.||.    |.|.......|.::....|..|:::|..::..|..   :.|.|   .|...||:
Human    80 AAPGHA----PGRDEAAPLNPGMYSQKAARPALEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQI 140

  Fly   217 --------------RKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQN 267
                          .|:.|||:||.|..||||.||..:||....|..:|..|.:.:.|:|.||||
Human   141 YPWMTKLHMSHETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQN 205

  Fly   268 RRTKWRRQT-AEEREA 282
            ||.||::.: .:.:||
Human   206 RRMKWKKDSKMKSKEA 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	36/109 (33%)
		Homeodomain	218..274	CDD:459649	28/55 (51%)
HOXC5	NP_061826.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..141		17/76 (22%)
		Antp-type hexapeptide	140..145		0/4 (0%)
		Homeodomain	156..212	CDD:459649	28/55 (51%)