Protein Alignment C15 and HOXB8

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_076921.1
• Gene: HOXB8 / 3218
• HGNCID: 5119
• Length: 243
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 59/230 - (25%)
• Similarity: 89/230 - (38%)
• Gaps: 62/230 - (26%)

  Fly   132 YKLATSIANSTY--GSAAALYSYPH-LYPSAAGG---HVLRV-------------PPQRTPLT-- 175
            ||...|:..:.|  |.|..|...|. :|..::||   |..::             |.|:.|..
Human    13 YKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQNPCAVA 77

  Fly   176 --------WALPPLHHAALAHQAVKD-------RLAAAFPIARRIGHPYQNRTPPK--------- 216
                    :...||...:|......|       :||||..:........|:.:|.:
Human    78 CHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQA 142

  Fly   217 ---RKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQT-- 276
               |::.|.:::|.|..||||.|....||....|..::..|.:|:.|||.||||||.||:::.
Human   143 AAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNK 207

  Fly   277 -------AEEREAERQAANRLMLSLQAEAISKGFA 304
                   .|:.|.|:|...|     ..||..:|.|
Human   208 DKFPSSKCEQEELEKQKLER-----APEAADEGDA 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	39/130 (30%)
		Homeodomain	218..274	CDD:459649	24/55 (44%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		0/4 (0%)
		Homeodomain	147..203	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..243		9/40 (23%)