Protein Alignment C15 and HOXB7

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_004493.3
• Gene: HOXB7 / 3217
• HGNCID: 5118
• Length: 217
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 65/229 - (28%)
• Similarity: 92/229 - (40%)
• Gaps: 62/229 - (27%)

  Fly    97 NHLLSSSPGSSSNNNNSGEKGEEKELLQQEDHDLAYKLATSIANST------YGS---AAALYSY 152
            |.|.|..|.|||.....                 |:...||.|.::      ||:   |:...|.
Human     8 NTLFSKYPASSSVFATG-----------------AFPEQTSCAFASNPQRPGYGAGSGASFAASM 55

  Fly   153 PHLYP--------SAAGGHV-----------LRVPPQRTPLTWALPPLHHAALAHQAVKDRLAAA 198
            ..|||        ||||.:.           :...|....|:...|.....|...:..:|...||
Human    56 QGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAA 120

  Fly   199 ---FPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQ 260
               |.|     :|:...:...||:.|.::||.|..||||.||..:||....|..:|..|.:|:.|
Human   121 ESNFRI-----YPWMRSSGTDRKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQ 180

  Fly   261 VKTWFQNRRTKWRRQ--------TAEER-EAERQ 285
            :|.||||||.||:::        |.::| |||.:
Human   181 IKIWFQNRRMKWKKENKTAGPGTTGQDRAEAEEE 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	38/102 (37%)
		Homeodomain	218..274	CDD:459649	27/55 (49%)
HOXB7	NP_004493.3	Antp-type hexapeptide	126..131		2/9 (22%)
		Homeodomain	138..194	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..217		5/21 (24%)