Protein Alignment C15 and HOXB4

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_076920.1
• Gene: HOXB4 / 3214
• HGNCID: 5115
• Length: 251
• Species: Homo sapiens
• Alignment Length: 185
• Identity: 59/185 - (31%)
• Similarity: 82/185 - (44%)
• Gaps: 36/185 - (19%)

  Fly   153 PHLYPSA----AGGHVLRVPPQRTPLTWALPPLH-------HAALAHQAVKDRLAAAFPIARRIG 206
            |.|.|.|    ..|.:|..|.||.....:.||..       |.:.:|.|.|:  ...:|..|::.
Human    87 PGLSPRAPAPPPAGALLPEPGQRCEAVSSSPPPPPCAQNPLHPSPSHSACKE--PVVYPWMRKVH 149

  Fly   207 ----HPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQN 267
                :|......|||.  ||::||.||.||||.||..:||....|..:|..|.:::.|:|.||||
Human   150 VSTVNPNYAGGEPKRS--RTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQN 212

  Fly   268 RRTKWRRQTAEEREAERQAANRLMLSLQAEAISKGFAPPSAPLGSQGGVNGAPLA 322
            ||.||::        :.:..|..:.|..|...:.|  ||..|       ||.|.|
Human   213 RRMKWKK--------DHKLPNTKIRSGGAAGSAGG--PPGRP-------NGGPRA 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	40/122 (33%)
		Homeodomain	218..274	CDD:459649	27/55 (49%)
HOXB4	NP_076920.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..134		12/46 (26%)
		Antp-type hexapeptide	141..146		1/4 (25%)
		Homeodomain	163..219	CDD:459649	29/57 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	220..251		11/40 (28%)