Protein Alignment C15 and HOXB1

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_002135.2
• Gene: HOXB1 / 3211
• HGNCID: 5111
• Length: 301
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 74/285 - (25%)
• Similarity: 99/285 - (34%)
• Gaps: 95/285 - (33%)

  Fly   102 SSPGSSSNNNNSGEKGEEKELLQQEDHDLAYKLATSIANSTYGSAAALYSY-------------- 152
            |||....|:....         ||....|.....:| |.|.|..||...||
Human    53 SSPAFQQNSGYPA---------QQPPSTLGVPFPSS-APSGYAPAACSPSYGPSQYYPLGQSEGD 107

  Fly   153 -PHLYPSAAGGHVLRV--------------PPQRTPL----TWALPPLHHAALAHQAVKDRLAAA 198
             .:.:||:.|..:..:              |||..|.    |.:..|.:...|:..  |:....:
Human   108 GGYFHPSSYGAQLGGLSDGYGAGGAGPGPYPPQHPPYGNEQTASFAPAYADLLSED--KETPCPS 170

  Fly   199 ---FPIARRIGHPYQNRTPPKRKKP-----------RTSFTRIQVAELEKRFHKQKYLASAERAA 249
               .|.||........|.|||..|.           ||:||..|:.||||.||..|||:.|.|..
Human   171 EPNTPTARTFDWMKVKRNPPKTAKVSEPGLGSPSGLRTNFTTRQLTELEKEFHFNKYLSRARRVE 235

  Fly   250 LARGLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQAANRLMLSLQAEAISKGFAPPSAPLGSQG 314
            :|..|::.:.|||.||||||.|.:::..||                      |..||:.|
Human   236 IAATLELNETQVKIWFQNRRMKQKKREREE----------------------GRVPPAPP----- 273

  Fly   315 GVNGAPLAALHGLQPWAEASHAAGC 339
               |.|..|.      .:||..:.|
Human   274 ---GCPKEAA------GDASDQSTC 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	42/132 (32%)
		Homeodomain	218..274	CDD:459649	29/66 (44%)
HOXB1	NP_002135.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..77		7/32 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..149		4/21 (19%)
		Antp-type hexapeptide	179..184		0/4 (0%)
		Homeodomain	207..260	CDD:459649	28/52 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	254..301		15/72 (21%)