Protein Alignment C15 and HOXA10

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_061824.3
• Gene: HOXA10 / 3206
• HGNCID: 5100
• Length: 410
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 57/269 - (21%)
• Similarity: 77/269 - (28%)
• Gaps: 125/269 - (46%)

  Fly    18 EVEEQEIHVDVDSDSRMSCGSGSDVDMDGGSCYDESETPLSESLQSEQTRSSSSENLPFSISRLL 82
            :...:|..:|......::||||      |||..||          .....||::|.|
Human   262 DAARKERALDSPPPPTLACGSG------GGSQGDE----------EAHASSSAAEEL-------- 302

  Fly    83 SKPFETSHHHHNNNNHLLSSSPGSSSNNNNSGEKGEEKELLQQEDHDLAYKLATSIANSTYGSAA 147
                                ||..|.::..|.||                   .|:.||...:||
Human   303 --------------------SPAPSESSKASPEK-------------------DSLGNSKGENAA 328

  Fly   148 ALYSYPHLYPSAAGGHVLRVPPQRTPLTWALPPLHHAALAHQAVKDRLAAAFPIARRIGHPYQNR 212
                                       .|.
Human   329 ---------------------------NWL----------------------------------- 331

  Fly   213 TPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQTA 277
            |....:|.|..:|:.|..||||.|....||....|..::|.:.:||.|||.||||||.|.::...
Human   332 TAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNR 396

  Fly   278 EEREAERQA 286
            |.|..|..|
Human   397 ENRIRELTA 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	30/91 (33%)
		Homeodomain	218..274	CDD:459649	25/55 (45%)
HOXA10	NP_061824.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..158
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..339		28/201 (14%)
		Homeodomain	337..393	CDD:459649	25/55 (45%)