Protein Alignment C15 and HOXA9

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_689952.1
• Gene: HOXA9 / 3205
• HGNCID: 5109
• Length: 272
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 61/261 - (23%)
• Similarity: 90/261 - (34%)
• Gaps: 80/261 - (30%)

  Fly    60 SLQSEQTRSSSSENLPFSISRLLSKPFETSHHHHNN------------------NNHLLSSSPG- 105
            |.||:.|...:|.| |...:...:.|....||||::                  ....|..:||
Human    55 SFQSKATVFGASWN-PVHAAGANAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTPGA 118

  Fly   106 -SSSNNNNSGEKGEEKELLQQ--------EDHDLAYKLATSIANSTYGS---------AAALYSY 152
             |.:...:|...|.:.|.|..        :.|.|      |:.:...||         :...:|.
Human   119 LSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTL------SLTDYACGSPPVDREKQPSEGAFSE 177

  Fly   153 PHLYPSAAGGHVLRVPPQRTPLTWALPPLHHAALAHQAVKDRLAAAFPIARRIGHPYQNRTPPKR 217
            .:. .:.:||....:.|......|    ||                   ||            ..
Human   178 NNA-ENESGGDKPPIDPNNPAANW----LH-------------------AR------------ST 206

  Fly   218 KKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREA 282
            :|.|..:|:.|..||||.|....||....|..:||.|.:|:.|||.||||||.|.::...:..:.
Human   207 RKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKD 271

  Fly   283 E 283
            |
Human   272 E 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	29/88 (33%)
		Homeodomain	218..274	CDD:459649	26/55 (47%)
HOXA9	NP_689952.1	Hox9_act	1..193	CDD:461369	28/145 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..198		6/43 (14%)
		Homeodomain	207..263	CDD:459649	26/55 (47%)