Protein Alignment C15 and HOXA5

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_061975.2
• Gene: HOXA5 / 3202
• HGNCID: 5106
• Length: 270
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 78/317 - (24%)
• Similarity: 114/317 - (35%)
• Gaps: 83/317 - (26%)

  Fly     4 HEEDDHE------------HENEHGEEVEEQEIHVDVDSDSRMSCGSGSDVDMDGGSCYDESETP 56
            |...||.            |...:|......::.|........  |||........|.   |..|
Human    22 HNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHF--GSGERARSYAASA---SAAP 81

  Fly    57 LSESLQSEQTRSSSSENLPFSISRLLSKPFETSHHHHNNNNHLLSSSPGSSSNNNN---SGEKGE 118
            .........|.:.|.:..|...|.:...|...|||...|:   ||:|.|:|::..:   |..:|.
Human    82 AEPRYSQPATSTHSPQPDPLPCSAVAPSPGSDSHHGGKNS---LSNSSGASADAGSTHISSREGV 143

  Fly   119 EKELLQQEDHDLAYKLATSIANSTYGSAAALYSYPHLYPSAAGGHVLRVPPQRTPLTWALPPLHH 183
            ......:||         :.|:|...||.:       .||.|       ||       |.|.:
Human   144 GTASGAEED---------APASSEQASAQS-------EPSPA-------PP-------AQPQI-- 176

  Fly   184 AALAHQAVKDRLAAAFPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERA 248
                           :|..|::...:.|...|:.|:.||::||.|..||||.||..:||....|.
Human   177 ---------------YPWMRKLHISHDNIGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRI 226

  Fly   249 ALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQAANRLMLSLQAEAISKGFAP 305
            .:|..|.:::.|:|.||||||.||::.            |:|. |:...|....|.|
Human   227 EIAHALCLSERQIKIWFQNRRMKWKKD------------NKLK-SMSMAAAGGAFRP 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	37/110 (34%)
		Homeodomain	218..274	CDD:459649	27/55 (49%)
HOXA5	NP_061975.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		31/135 (23%)
		Antp-type hexapeptide	176..181		1/21 (5%)
		Homeodomain	196..252	CDD:459649	27/55 (49%)