Protein Alignment C15 and HOXA4

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_002132.3
• Gene: HOXA4 / 3201
• HGNCID: 5105
• Length: 320
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 77/291 - (26%)
• Similarity: 108/291 - (37%)
• Gaps: 84/291 - (28%)

  Fly    85 PFETSHHHHNNNNHLLSSSPGSSSNNNNSGEKGEEKELLQQ---------EDHDLAYKLATSIAN 140
            |||....|..:..  ....||.............:...|||         .:...:|....:...
Human    19 PFEEYAQHSGSGG--ADGGPGGGPGYQQPPAPPTQHLPLQQPQLPHAGGGREPTASYYAPRTARE 81

  Fly   141 STYGSAAALY--------SYPHLY---------------PSAAGG--------HVLR-------- 166
            ..| .|||||        :||:.|               |:.|.|        |||:
Human    82 PAY-PAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPPAQAKGPAHGLHASHVLQPQLPPPLQ 145

  Fly   167 ---VPP------QRTPLTWALP--------PLHHAALAHQAVKDRLAAAFPIARRIG----HPYQ 210
               |||      :..|.|..:|        ||..|..:...:|.:....:|..::|.    :|..
Human   146 PRAVPPAAPRRCEAAPATPGVPAGGSAPACPLLLADKSPLGLKGKEPVVYPWMKKIHVSAVNPSY 210

  Fly   211 NRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQ 275
            |...|||.  ||::||.||.||||.||..:||....|..:|..|.:::.|||.||||||.||::
Human   211 NGGEPKRS--RTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKK- 272

  Fly   276 TAEEREAERQAANRLMLSLQAEAISKGFAPP 306
                   :.:..|..|.|..:.:.|.|  ||
Human   273 -------DHKLPNTKMRSSNSASASAG--PP 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	42/115 (37%)
		Homeodomain	218..274	CDD:459649	28/55 (51%)
HOXA4	NP_002132.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..77		10/59 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..168		13/66 (20%)
		Antp-type hexapeptide	194..199		1/4 (25%)
		Homeodomain	216..272	CDD:459649	30/57 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	273..320		7/24 (29%)