Protein Alignment C15 and HMX2

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_005510.1
• Gene: HMX2 / 3167
• HGNCID: 5018
• Length: 273
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 69/195 - (35%)
• Similarity: 92/195 - (47%)
• Gaps: 44/195 - (22%)

  Fly   157 PSAAGGHVLRVPP---QRTPLTWALPPLHHAALAHQAVKDRLAAAFPIARRIGHPYQNRTPPK-- 216
            |..:||.    .|   :|||.   |.|.|.   ..:..|:||..|       |.|......|:
Human    92 PKGSGGS----GPGGLERTPF---LSPSHS---DFKEEKERLLPA-------GSPSPGSERPRDG 139

  Fly   217 ---------RKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKW 272
                     :||.||.|:|.||.:||..|..::||:|:|||.||..|::|:.||||||||||.||
Human   140 GAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKW 204

  Fly   273 RRQTAEEREAERQA---ANRLM--------LSLQAEAISKGFAPPSAPLGSQG-GVNGAPLAALH 325
            :||.:.|.||...|   |..|:        .||....:.:..|.| |||...| .::..||..|:
Human   205 KRQLSAELEAANMAHASAQTLVSMPLVFRDSSLLRVPVPRSLAFP-APLYYPGSNLSALPLYNLY 268

  Fly   326  325
            Human   269  268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	53/141 (38%)
		Homeodomain	218..274	CDD:459649	33/55 (60%)
HMX2	NP_005510.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		18/76 (24%)
		Homeodomain	150..206	CDD:459649	33/55 (60%)