Protein Alignment C15 and nkx2.2a

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_571497.2
• Gene: nkx2.2a / 30697
• ZFINID: ZDB-GENE-980526-403
• Length: 273
• Species: Danio rerio
• Alignment Length: 251
• Identity: 56/251 - (22%)
• Similarity: 90/251 - (35%)
• Gaps: 100/251 - (39%)

  Fly    43 DMDGGSCYDESETPLSESLQSE----QTRSSSSENLPFSISRLLSKPFETSHHHHNNNN------ 97
            |.:|.....|.:|..||:.::.    |:...:.:|||      |..||     :.|::|
Zfish    27 DEEGSITGTEEDTEGSEATKTPGVLVQSPLENVQNLP------LKNPF-----YDNSDNPYTRWL 80

  Fly    98 ----HLLSSSPGSSSNNNNSGEKGEEKELLQQEDHDLAYKLATSIANSTYGSAAALYSYPHLYPS 158
                .:..|..|.|:|:.::..|..|....:..|:|.        ..|:.||.:.
Zfish    81 ATTDSIQYSLHGLSANSQDTSAKSPEPSADESPDNDK--------ETSSNGSDSG---------- 127

  Fly   159 AAGGHVLRVPPQRTPLTWALPPLHHAALAHQAVKDRLAAAFPIARRIGHPYQNRTPPKRKKPRTS 223
                                                                     |::|.|..
Zfish   128 ---------------------------------------------------------KKRKRRVL 135

  Fly   224 FTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEE 279
            |::.|..|||:||.:|:||::.||..||..:::|..|||.||||.|.|.:|..||:
Zfish   136 FSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEK 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	30/84 (36%)
		Homeodomain	218..274	CDD:459649	26/55 (47%)
nkx2.2a	NP_571497.2	COG5576	93..218	CDD:227863	39/174 (22%)
		Homeodomain	130..186	CDD:459649	26/55 (47%)