Protein Alignment C15 and tlx1

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_739571.1
• Gene: tlx1 / 266964
• ZFINID: ZDB-GENE-021021-2
• Length: 301
• Species: Danio rerio
• Alignment Length: 357
• Identity: 130/357 - (36%)
• Similarity: 164/357 - (45%)
• Gaps: 103/357 - (28%)

  Fly    10 EHENEHGEEVEEQEIHVDVDSDSRMSCGSGSDVDMDGGSCYDESETPLSESLQSEQTRSSSSENL 74
            :|...|..:.....|...:|....         :.|.|||               ...:...::|
Zfish     2 DHMGAHLHQTHADTISFGIDQILN---------NADQGSC---------------MITNPRMQDL 42

  Fly    75 PFSISRLLSKPFETSHHHHNNNNHLLSSSPGSSSNNNNSGEKGEEKELLQQEDHDLAYKLATSIA 139
            .:.:..::|..:.|...::|.||        ||..|.||...|...           ..|..::.
Zfish    43 DYGLGCIVSTAYNTMTGNYNVNN--------SSGYNGNSCSVGSYN-----------MNLGANVN 88

  Fly   140 NSTYGSAAALYSYPHLYPSAAGGHVLRVPPQRTPLTWALPPLH--HAALAHQA------------ 190
            .:...|:.                |:|||..|        ||.  |:::...|
Zfish    89 GNCLNSSG----------------VIRVPAHR--------PLGSVHSSIPTSAATVPSMGSMGTI 129

  Fly   191 -----------------VKDRLAAA---FPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKR 235
                             .|||...|   |.:.||||||||||||||:|||||||||:|:.|||||
Zfish   130 NNLTGLTFPWMESNRRYTKDRFTVALSPFTVTRRIGHPYQNRTPPKKKKPRTSFTRLQICELEKR 194

  Fly   236 FHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQAANRLMLSLQAEAIS 300
            ||:|||||||||||||:.||||||||||||||||||||||||||||||||.|||:::.||.||..
Zfish   195 FHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAERQQANRILMQLQQEAFQ 259

  Fly   301 KGFAPPSAPLGSQGGVNGAPLAALHGLQPWAE 332
            |....|..|  ....::.:.|.||..||||.|
Zfish   260 KTINQPVTP--DPICLHNSSLFALQNLQPWTE 289

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	88/121 (73%)
		Homeodomain	218..274	CDD:459649	49/55 (89%)
tlx1	NP_739571.1	Homeodomain	177..233	CDD:459649	49/55 (89%)