Protein Alignment C15 and EMX2

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_004089.1
• Gene: EMX2 / 2018
• HGNCID: 3341
• Length: 252
• Species: Homo sapiens
• Alignment Length: 190
• Identity: 68/190 - (35%)
• Similarity: 88/190 - (46%)
• Gaps: 41/190 - (21%)

  Fly   135 ATSIANST--------YGSAAA------LYSYPHLYPSAAGGH-------VLRVPPQRTPLTWAL 178
            |.|.|||:        :.||||      :||.|.|..:.|..|       |..|||........|
Human    35 ALSYANSSPINPFLNGFHSAAAAAAGRGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAHPL 99

  Fly   179 PPLH--HAALAHQAVKDRLAAAFPIA----RRIGHPYQ-NRTPP-----------KRKKPRTSFT 225
            |..|  |...|.|. :|. :..:|..    |.:||.:| |.|.|           |.|:.||:|:
Human   100 PSSHSPHPLFASQQ-RDP-STFYPWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFS 162

  Fly   226 RIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQ 285
            ..|:..||..|.|..|:..|||..||..|.:|:.|||.||||||||::||..||..::.|
Human   163 PSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQ 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	42/106 (40%)
		Homeodomain	218..274	CDD:459649	28/55 (51%)
EMX2	NP_004089.1	Homeodomain	155..211	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..252		4/11 (36%)