Protein Alignment C15 and Pdx1

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_032840.1
• Gene: Pdx1 / 18609
• MGIID: 102851
• Length: 284
• Species: Mus musculus
• Alignment Length: 232
• Identity: 63/232 - (27%)
• Similarity: 92/232 - (39%)
• Gaps: 70/232 - (30%)

  Fly   153 PHLYPSAAGGHVLRVPPQRTPLTWALPPL-----------HH----AALAHQ------------- 189
            |..:.|:.|......||..:|  :.:|||           ||    ..|||.
Mouse    47 PPQFTSSLGSLEQGSPPDISP--YEVPPLASDDPAGAHLHHHLPAQLGLAHPPPGPFPNGTEPGG 109

  Fly   190 -AVKDRLAAAFPIARRI-GHPYQNR--------TPPKRKKPRTSFTRIQVAELEKRFHKQKYLAS 244
             ...:|:...||..:.. .|.::.:        .|.:.|:.||::||.|:.||||.|...||::.
Mouse   110 LEEPNRVQLPFPWMKSTKAHAWKGQWAGGAYTAEPEENKRTRTAYTRAQLLELEKEFLFNKYISR 174

  Fly   245 AERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEER------------EAERQAANRLMLSLQAE 297
            ..|..||..|.:|:..:|.||||||.||:::..::|            |.|:..
Mouse   175 PRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRSSGTPSGGGGGEEPEQDC----------- 228

  Fly   298 AISKG----FAPPSAPLGSQGGV-NGAPLAALHGLQP 329
            |::.|    ..||..|.|  |.| .|.|.|...||.|
Mouse   229 AVTSGEELLAVPPLPPPG--GAVPPGVPAAVREGLLP 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	40/143 (28%)
		Homeodomain	218..274	CDD:459649	27/55 (49%)
Pdx1	NP_032840.1	Transactivation domain. /evidence=ECO:0000250	13..73		7/27 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..116		14/70 (20%)
		Antp-type hexapeptide	119..124		2/4 (50%)
		Homeodomain	148..204	CDD:459649	27/55 (49%)
		Nuclear localization signal	198..204		4/5 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..284		18/75 (24%)