Protein Alignment C15 and Nkx2-6

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_035050.2
• Gene: Nkx2-6 / 18092
• MGIID: 97351
• Length: 289
• Species: Mus musculus
• Alignment Length: 295
• Identity: 79/295 - (26%)
• Similarity: 110/295 - (37%)
• Gaps: 72/295 - (24%)

  Fly    68 SSSSENLPFSISRLL--------SKPFETSHHHHNNNNHLLSSSPGSSSNNNNSGEKGEEKELLQ 124
            ||...:.|||::.:|        ||.......|.|      ...|.....|..||       ..:
Mouse     3 SSPVASTPFSVADILRLECQQKDSKTLSQWELHRN------PVKPRYLRMNQESG-------WFE 54

  Fly   125 QEDHDLAYKLATSIANSTYGSAAALYSYPHLYPSAAGGHVLRVPPQRTPLTWALPPLHHAALAHQ 189
            ..|...|...     ..|:.:...:.|.|...|....|.:.|: ..|.|:|
Mouse    55 SSDRAQAVPF-----RCTWETVLEMGSNPVGEPQTPPGTISRL-GARNPMT-------------- 99

  Fly   190 AVKDRLAAAFPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGL 254
               ||.........|.|.|...||.|:||. |..|::.||..||:||.:|:||.:.||..||..|
Mouse   100 ---DRGVGNLSGDMRRGGPVSTRTRPQRKS-RVLFSQAQVLALERRFKQQRYLTAPEREHLASAL 160

  Fly   255 KMTDAQVKTWFQNRRTKWRRQTAEER--------EAERQAANRLMLS----LQAEAISKGFAPP- 306
            ::|..|||.||||||.|.:.|..::.        ...|.|...|:|.    |..:..:  |..|
Mouse   161 QLTSTQVKIWFQNRRYKSKSQRQDQTLELAGHPLAPRRVAVPVLVLDGKPCLDPDVAA--FLGPY 223

  Fly   307 --SAPLGSQGGVNGAPLAALHGLQPWAEASHAAGC 339
              ::|....||..|.|.          :||:|:.|
Mouse   224 KATSPYSCFGGYAGTPY----------DASYASRC 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	44/133 (33%)
		Homeodomain	218..274	CDD:459649	28/55 (51%)
Nkx2-6	NP_035050.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..125		16/67 (24%)
		Homeodomain	124..179	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	259..289