Protein Alignment C15 and Nkx2-3

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_032725.1
• Gene: Nkx2-3 / 18089
• MGIID: 97348
• Length: 362
• Species: Mus musculus
• Alignment Length: 335
• Identity: 82/335 - (24%)
• Similarity: 126/335 - (37%)
• Gaps: 102/335 - (30%)

  Fly    75 PFSISRLLSKPFETSHHHHNNNNHL-------LSSSPG--SSSNNNNSGEKGEEKELLQQEDHDL 130
            |||:..:|:  .|...|.|  ..||       ..|:|.  :::......:.|||.|  ::|...|
Mouse    11 PFSVKDILN--LEQQRHFH--GAHLQAELEQHFHSAPCMLATAEGTQFSDAGEEDE--EEEGEKL 69

  Fly   131 AYKLATSIANSTYGSAAALYSYPH-LYPSAAGGHVLRVPPQRTPLTWALPPLHHAALAHQAVKDR 194
            :|..:.:.|.....|.....||.| :...|..|     |.::               ..:.|.:|
Mouse    70 SYLNSLAAAEGHGDSGLCPQSYVHTVLRDACSG-----PKEQ---------------EEEVVSER 114

  Fly   195 LAAAFPIARRIGHPYQNRT--------PPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALA 251
            ...:..:.:.:......:|        |..|:|||..|::.||.|||:||.:|:||::.||..||
Mouse   115 SQKSCQLKKSLEAAGDCKTSEDGERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLA 179

  Fly   252 RGLKMTDAQVKTWFQNRRTKWRRQTAEEREAE----------RQAANRLML-------------- 292
            ..||:|..|||.||||||.|.:|| .:::..|          |:.|..:::
Mouse   180 SSLKLTSTQVKIWFQNRRYKCKRQ-RQDKSLELGTHAPPPPPRRVAVPVLVRDGKPCVTPSAQTY 243

  Fly   293 -----------------------SLQAEAISKGFAPPSA----------PLGSQGGVNGAPLAAL 324
                                   |..|.|.:...|..:|          |.|..||..|...||.
Mouse   244 GSPYGVGAGAYSYNSFPAYGYGNSAAAAAAAAAAAAAAAAYSGSYGCAYPTGGGGGGGGTASAAT 308

  Fly   325 HGLQPWAEAS 334
            ..:||...|:
Mouse   309 TAMQPACSAT 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	46/183 (25%)
		Homeodomain	218..274	CDD:459649	31/55 (56%)
Nkx2-3	NP_032725.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..149		4/22 (18%)
		Homeodomain	146..202	CDD:459649	31/55 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..222		2/19 (11%)