Protein Alignment C15 and DLX5

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_005212.1
• Gene: DLX5 / 1749
• HGNCID: 2918
• Length: 289
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 78/283 - (27%)
• Similarity: 114/283 - (40%)
• Gaps: 82/283 - (28%)

  Fly    85 PFETS--HHHHNNNNHLLSSSPGSSSN-------------NNNSGEKGEEKELLQQEDHDLAYKL 134
            ||:||  .||.:..:..|..|..:.|:             :..|...|:.....|.:.|.:
Human    20 PFQTSAAMHHPSQESPTLPESSATDSDYYSPTGGAPHGYCSPTSASYGKALNPYQYQYHGV---- 80

  Fly   135 ATSIANSTYGS----AAALYSYP---HLYPSAAGGHVLRVPPQRTPLTWALPPLHHAALAHQAVK 192
                 |.:.||    |.|.|||.   |.|    ||...|||                :..:|..|
Human    81 -----NGSAGSYPAKAYADYSYASSYHQY----GGAYNRVP----------------SATNQPEK 120

  Fly   193 DRLAAAFPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMT 257
            :   ...|..|.:     |..|.|.:||||.::..|:|.|::||.|.:|||..|||.||..|.:|
Human   121 E---VTEPEVRMV-----NGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLT 177

  Fly   258 DAQVKTWFQNRRTKWRR--QTAE------EREAERQAANRLMLSLQAEAISKGFAPPSAPLGSQG 314
            ..|||.||||:|:|.::  :..|      ...::..|.|    |.|:.|:.:       |.||..
Human   178 QTQVKIWFQNKRSKIKKIMKNGEMPPEHSPSSSDPMACN----SPQSPAVWE-------PQGSSR 231

  Fly   315 GVNGAPLAALHGLQPWAEASHAA 337
            .::..|    |...|.:..|.|:
Human   232 SLSHHP----HAHPPTSNQSPAS 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	43/126 (34%)
		Homeodomain	218..274	CDD:459649	29/55 (53%)
DLX5	NP_005212.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49		9/28 (32%)
		DLL_N	32..118	CDD:463567	22/114 (19%)
		Homeodomain	138..194	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	198..251		14/68 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..289