Protein Alignment C15 and DLX1

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_835221.2
• Gene: DLX1 / 1745
• HGNCID: 2914
• Length: 255
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 75/287 - (26%)
• Similarity: 116/287 - (40%)
• Gaps: 51/287 - (17%)

  Fly    55 TPLSESLQSEQTRSSSSENLPFSISRLLSKPFETSHHHHNNNNHLLSSSPGSSSNNNNSGEKGEE 119
            |.:.|||.|..  |..:..:.|........|...||.|:  :.|.|.|:..|..:...|......
Human     4 TTMPESLNSPV--SGKAVFMEFGPPNQQMSPSPMSHGHY--SMHCLHSAGHSQPDGAYSSASSFS 64

  Fly   120 KELLQQEDHDLAYKLATSI---ANSTYGSAAALYSYPHLYPSAAGGHVLRVPPQRTPLTWALPPL 181
            :        .|.|....|:   |:|.|  .:::.|||
Human    65 R--------PLGYPYVNSVSSHASSPY--ISSVQSYP---------------------------- 91

  Fly   182 HHAALAHQAVKDRLA-AAFPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASA 245
            ..|:||...::|..| :........|....|....|.:||||.::.:|:..|.:||.:.:|||..
Human    92 GSASLAQSRLEDPGADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALP 156

  Fly   246 ERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREA-ERQA-ANRLMLSLQAEAISKGFAPPSA 308
            |||.||..|.:|..|||.||||:|:|:::...:...| |..| ||...||..:..:..|:.|.|:
Human   157 ERAELAASLGLTQTQVKIWFQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWNPNSS 221

  Fly   309 PLGSQGGVNGAPLAALHGLQPWAEASH 335
            .....||..|:.:.:   ...|..::|
Human   222 SGKGSGGNAGSYIPS---YTSWYPSAH 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	41/121 (34%)
		Homeodomain	218..274	CDD:459649	27/55 (49%)
DLX1	NP_835221.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		9/35 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..118		4/22 (18%)
		Homeodomain	129..185	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..230		7/25 (28%)