Protein Alignment C15 and tlx2

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: XP_005173139.1
• Gene: tlx2 / 170781
• ZFINID: ZDB-GENE-020208-1
• Length: 309
• Species: Danio rerio
• Alignment Length: 315
• Identity: 133/315 - (42%)
• Similarity: 155/315 - (49%)
• Gaps: 102/315 - (32%)

  Fly    89 SHHHHN----NNNHLLSSSPGSSSNNNNSGEKGEEKELLQQEDHDLAYKLATSIANSTYGSAAAL 149
            :|..|.    ..:.:|:.|..|||.            :|.....|..|.|..::.|
Zfish    12 THQQHETISFGIDQILNGSDQSSSC------------MLPSRTGDPDYALTPNVYN--------- 55

  Fly   150 YSYPHLYPS---AAG--------------------------GHVLRVPPQRTPLTWALPPLHHAA 185
             .|..:||:   |||                          |.|:|||..|     .:||..|..
Zfish    56 -GYNSMYPACSMAAGLAGSYNVNMNMNVSMNMNVNVNSGNAGGVIRVPAHR-----PMPPAPHQP 114

  Fly   186 LA---------------------------------HQAVKDRLAAA---FPIARRIGHPYQNRTP 214
            .|                                 .:..||||.||   |.:.||||||||||||
Zfish   115 TAGHPPSIAAGIPTMPTVPSMGSPHSFTFPWMESSRRFAKDRLTAALSPFSVTRRIGHPYQNRTP 179

  Fly   215 PKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEE 279
            ||||||||||:|:|:.|||||||:||||||||||.||:.||||||||||||||||||||||||||
Zfish   180 PKRKKPRTSFSRVQICELEKRFHRQKYLASAERATLAKALKMTDAQVKTWFQNRRTKWRRQTAEE 244

  Fly   280 REAERQAANRLMLSLQAEAISKGFAPP--SAPLGSQGGVNGAPLAALHGLQPWAE 332
            ||||||.||||||.||.||..|..:.|  ..||    .::.:.|.||..||||||
Zfish   245 REAERQQANRLMLQLQQEAFQKTLSQPLQQDPL----CLHNSSLYALQNLQPWAE 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	92/123 (75%)
		Homeodomain	218..274	CDD:459649	47/55 (85%)
tlx2	XP_005173139.1	Homeodomain	183..239	CDD:459649	47/55 (85%)