Protein Alignment C15 and Hoxd3

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_034598.2
• Gene: Hoxd3 / 15434
• MGIID: 96207
• Length: 433
• Species: Mus musculus
• Alignment Length: 266
• Identity: 64/266 - (24%)
• Similarity: 93/266 - (34%)
• Gaps: 108/266 - (40%)

  Fly   137 SIANSTYGSAAALYSYPHL--------------YPSAA-------------------GGHVLR-- 166
            |.|..|||     ||.||.              |||:|                   .|..:|
Mouse    35 SKATDTYG-----YSTPHQPYPPPAAANSLDSDYPSSACSIQSSAPLRAPAHKGAELNGSCMRPG 94

  Fly   167 -----------------------VPPQRTPLTWALPPLH----HAALAHQAVKDRLAAA------ 198
                                   .||...|.|  |||..    .:.:..:..|..|:|:
Mouse    95 TGNSQGGGGGNQPPGLNSEQQPPQPPPPPPPT--LPPSSPTNPGSGVPAKKTKGGLSASSSSSTI 157

  Fly   199 ----FPIARR-------------IGHPYQNRTP--PKRKKPRTSFTRIQVAELEKRFHKQKYLAS 244
                ||..:.             .|...::::|  |..|:.||::|..|:.||||.||..:||..
Mouse   158 SKQIFPWMKESRQNSKQKNSCATSGENCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCR 222

  Fly   245 AERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEEREAERQAANRLMLSLQAEAISKGFAPPSAP 309
            ..|..:|..|.:|:.|:|.||||||.|:::.         |.|..::.|...::..:     |.|
Mouse   223 PRRVEMANLLNLTERQIKIWFQNRRMKYKKD---------QKAKGILHSPAGQSPER-----SPP 273

  Fly   310 LGSQGG 315
            ||...|
Mouse   274 LGGAAG 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	39/143 (27%)
		Homeodomain	218..274	CDD:459649	26/55 (47%)
Hoxd3	NP_034598.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..198		25/155 (16%)
		Antp-type hexapeptide	161..166		2/4 (50%)
		Homeodomain	196..252	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	258..280		6/27 (22%)
		DUF4074	370..431	CDD:463833
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	401..433