Protein Alignment C15 and Hhex

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_032271.1
• Gene: Hhex / 15242
• MGIID: 96086
• Length: 271
• Species: Mus musculus
• Alignment Length: 163
• Identity: 54/163 - (33%)
• Similarity: 73/163 - (44%)
• Gaps: 39/163 - (23%)

  Fly   128 HDLAYKLATSIANSTYGSAAALYSYPHL---YPSAAGGHVLRVPPQRTPLTWALPPLHHAALAHQ 189
            |..|..||.:...|.:|  ..||.:|..   |..|    :||..|...||.|:
Mouse    82 HHPAAALAAAYGPSGFG--GPLYPFPRTVNDYTHA----LLRHDPLGKPLLWS------------ 128

  Fly   190 AVKDRLAAAFPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGL 254
                              |:..|...|||..:..|:..|..||||:|..||||:..||..||:.|
Mouse   129 ------------------PFLQRPLHKRKGGQVRFSNDQTVELEKKFETQKYLSPPERKRLAKML 175

  Fly   255 KMTDAQVKTWFQNRRTKWRRQTAEEREAERQAA 287
            ::::.||||||||||.||||...|..::.::.|
Mouse   176 QLSERQVKTWFQNRRAKWRRLKQENPQSNKKDA 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	37/92 (40%)
		Homeodomain	218..274	CDD:459649	29/55 (53%)
Hhex	NP_032271.1	Interaction with SOX13. /evidence=ECO:0000250|UniProtKB:Q03014	1..138		19/91 (21%)
		Required for WNT signaling induction. /evidence=ECO:0000250|UniProtKB:Q03014	138..271		34/71 (48%)
		Homeodomain	143..195	CDD:459649	28/51 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..271		3/14 (21%)