Protein Alignment C15 and Dlx2

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_034184.1
• Gene: Dlx2 / 13392
• MGIID: 94902
• Length: 332
• Species: Mus musculus
• Alignment Length: 307
• Identity: 81/307 - (26%)
• Similarity: 116/307 - (37%)
• Gaps: 92/307 - (29%)

  Fly    88 TSHHHHNNNNHLLSSSPGSSSN---NNNSGEKGEEKELL-------------QQED--------- 127
            :::|.|........:.||.:||   :|:|..|.:|...|             ||..
Mouse    21 STYHQHQQPPSGAGAGPGGNSNSSSSNSSLHKPQESPTLPVSTATDSSYYTNQQHPAGGGGGGAS 85

  Fly   128 ---HDLAYKLATSIANSTYGSAAALY--SYPHLYPSAAGGHVLRVPPQRTPLTWALPPLHHAALA 187
               |..:|:...|..|:...||.:.|  .|...|.|.|            |...:..|::
Mouse    86 PYAHMGSYQYHASGLNNVSYSAKSSYDLGYTAAYTSYA------------PYGTSSSPVN----- 133

  Fly   188 HQAVKDRLAAAFPIARRIGHPYQNRTPPKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALAR 252
            ::..|:.|.....|.        |..|.|.:||||.::..|:|.|::||.|.:|||..|||.||.
Mouse   134 NEPDKEDLEPEIRIV--------NGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAA 190

  Fly   253 GLKMTDAQVKTWFQNRRTKWRRQ-TAEEREAERQAANRLMLSLQAEAISKGFAPP-SAP------ 309
            .|.:|..|||.||||||:|:::. .:.|...|:...        |.|.....:|| |||
Mouse   191 SLGLTQTQVKIWFQNRRSKFKKMWKSGEIPTEQHPG--------ASASPPCASPPVSAPASWDFG 247

  Fly   310 ----------------LGSQGGVNGAPLAALHGLQPW-----AEASH 335
                            .||.|....:..:|..|..||     ..|||
Mouse   248 APQRMAGGGPGSGGGGAGSSGSSPSSAASAFLGNYPWYHQASGSASH 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	45/142 (32%)
		Homeodomain	218..274	CDD:459649	30/55 (55%)
Dlx2	NP_034184.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..83		13/61 (21%)
		DLL_N	54..135	CDD:463567	17/97 (18%)
		Homeodomain	156..212	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..272		11/60 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	304..332