Protein Alignment C15 and Cdx1

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_034010.3
• Gene: Cdx1 / 12590
• MGIID: 88360
• Length: 268
• Species: Mus musculus
• Alignment Length: 247
• Identity: 68/247 - (27%)
• Similarity: 90/247 - (36%)
• Gaps: 86/247 - (34%)

  Fly   142 TY---GSAAALYSYPHLYPSAAG-GHVLRVPPQRTPLTWALPPLHHAALAHQAVKDRLAAAF--- 199
            ||   |.|.|    |..||..|| .||  .|....|.|||.|        ..|.||..|||:
Mouse    29 TYAPPGPAPA----PPQYPDFAGYTHV--EPAPAPPPTWAAP--------FPAPKDDWAAAYGPG 79

  Fly   200 --------------------PI-----------ARRIGHPYQNRTP--PKR-------------- 217
                                |:           |:.:|.|....:|  |:|
Mouse    80 PTASAASPAPLAFGPPPDFSPVPAPPGPGPGILAQSLGAPGAPSSPGAPRRTPYEWMRRSVAAAG 144

  Fly   218 ----------KKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKW 272
                      .|.|..:|..|..||||.||..:|:....::.||..|.:|:.|||.||||||.|
Mouse   145 GGGSGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAK- 208

  Fly   273 RRQTAEEREAERQAANRLMLSLQAEAISKGFAPPSAPLGS----QGGVNGAP 320
            .|:..::::.::|......|.|..:...   .|...||||    ..|:.|.|
Mouse   209 ERKVNKKKQQQQQPLPPTQLPLPLDGTP---TPSGPPLGSLCPTNAGLLGTP 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	44/182 (24%)
		Homeodomain	218..274	CDD:459649	25/55 (45%)
Cdx1	NP_034010.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		31/136 (23%)
		Caudal_act	13..140	CDD:461413	31/124 (25%)
		Homeodomain	156..211	CDD:459649	25/55 (45%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	157..178		9/20 (45%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	196..207		8/10 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..268		12/52 (23%)