Protein Alignment C15 and CDX4

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: NP_005184.1
• Gene: CDX4 / 1046
• HGNCID: 1808
• Length: 284
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 62/276 - (22%)
• Similarity: 97/276 - (35%)
• Gaps: 87/276 - (31%)

  Fly   103 SPGSSSNNNNSGEKGEEKELLQQEDHDLAYKLATSIANSTYGSAAAL---YSYPHL------YPS 158
            |||........|..|.                .:.:..|.:.:|.|.   ..|||:      :||
Human    20 SPGGDGTAGTGGTGGG----------------GSPMPASNFAAAPAFSHYMGYPHMPSMDPHWPS 68

  Fly   159 AAGGHVLRVPPQRTPLTWALPPLHHAALAHQAVKDRLA--AAF---------PI----------- 201
            .........||:.   .|::.|...:.:....|.|..:  |||         |:
Human    69 LGVWGSPYSPPRE---DWSVYPGPSSTMGTVPVNDVTSSPAAFCSTDYSNLGPVGGGTSGSSLPG 130

  Fly   202 ------------ARRIGHPYQNRTPP---------------KRKKPRTSFTRIQVAELEKRFHKQ 239
                        |.:...|.::|..|               .::|.|..:|..|..||||.||..
Human   131 QAGGSLVPTDAGAAKASSPSRSRHSPYAWMRKTVQVTGKTRTKEKYRVVYTDHQRLELEKEFHCN 195

  Fly   240 KYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQTAEE-REAERQAANRLMLSLQAEAISKG- 302
            :|:....::.||..|.:::.|||.||||||.|.|:...:: .:.|....:   :...:::||.|
Human   196 RYITIQRKSELAVNLGLSERQVKIWFQNRRAKERKMIKKKISQFENSGGS---VQSDSDSISPGE 257

  Fly   303 -----FAPPSAPLGSQ 313
                 |..|||..|.|
Human   258 LPNTFFTTPSAVRGFQ 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	43/174 (25%)
		Homeodomain	218..274	CDD:459649	24/55 (44%)
CDX4	NP_005184.1	Caudal_act	13..170	CDD:461413	27/168 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..40		5/35 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..155		3/34 (9%)
		Homeodomain	175..230	CDD:459649	24/54 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..259		4/23 (17%)