Protein Alignment C15 and nkx2-1

DIOPT Version :10

• Sequence 1: NP_476873.2
• Gene: C15 / 42544
• FlyBaseID: FBgn0004863
• Length: 339
• Species: Drosophila melanogaster
• Sequence 2: XP_002935383.1
• Gene: nkx2-1 / 100135015
• XenbaseID: XB-GENE-485985
• Length: 346
• Species: Xenopus tropicalis
• Alignment Length: 312
• Identity: 78/312 - (25%)
• Similarity: 120/312 - (38%)
• Gaps: 94/312 - (30%)

  Fly    69 SSSENLPFSISRLLSKPFETSH------------------------------HHHNNNN------ 97
            |.....|||:|.:|| |.|.|:                              |...:|.
 Frog     4 SPKHTTPFSVSDILS-PLEESYKKVAMESAGLGAPLSAAYRQSQVSQASMQQHGMGHNGPVSAAY 67

  Fly    98 HLLSSSPGSSSN-------NNNSGEKGEEKELLQQEDHDLAYKLATSIANSTYGSAAALYSYPHL 155
            |:.::.....|:       |.|.|..|...||...:|         ::.||
 Frog    68 HMTAAGVPQLSHTTMGGYCNGNLGNLGNMSELPPYQD---------TMRNS-------------- 109

  Fly   156 YPSAAGGHVLRVPPQRTPLTWALPP---LHHAALAHQAVKDRLAAAFPIARRIGHPYQNRTP--- 214
              ||.|.:.....|:.:.::..:.|   ::...|.:..             .:|...::.||
 Frog   110 --SATGWYGANPDPRFSTISRFMGPSSGMNMGGLGNMG-------------SLGDVGKSMTPLQA 159

  Fly   215 -PKRKKPRTSFTRIQVAELEKRFHKQKYLASAERAALARGLKMTDAQVKTWFQNRRTKWRRQTAE 278
             |:||: |..|::.||.|||:||.:||||::.||..||..:.:|..|||.||||.|.|.:|| |:
 Frog   160 TPRRKR-RVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQ-AK 222

  Fly   279 EREAERQAANRLMLSLQAEAISKGFAPPSAPLGS--QGGVNGAPLAALHGLQ 328
            ::.|::|.........|.::..:...|.....|.  |.|.| .|.|||...|
 Frog   223 DKAAQQQMQQDNSSCQQQQSPRRVAVPVLVKDGKPCQAGSN-TPTAALQSHQ 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
C15	NP_476873.2	COG5576	<196..315	CDD:227863	42/124 (34%)
		Homeodomain	218..274	CDD:459649	28/55 (51%)
nkx2-1	XP_002935383.1	Homeodomain	163..219	CDD:459649	29/56 (52%)