Protein Alignment Fancm and radD

DIOPT Version :10

• Sequence 1: NP_650971.2
• Gene: Fancm / 42543
• FlyBaseID: FBgn0038889
• Length: 1489
• Species: Drosophila melanogaster
• Sequence 2: NP_416689.1
• Gene: radD / 945529
• ECOCYCID: EG12045
• Length: 586
• Species: Escherichia coli
• Alignment Length: 686
• Identity: 144/686 - (20%)
• Similarity: 228/686 - (33%)
• Gaps: 210/686 - (30%)

  Fly    58 LRSYQQTIVQSAL--FKN----TLVVLPTGLGKTFIAAVVMYNFYRWYPKGKIVFMAPTRPLVSQ 116
            ||.|||..|.:.|  |:.    .::|||||.||:.:.|.:..     ..:|:::.:|..:.||:|
E. coli     5 LRPYQQEAVDATLNHFRRHKTPAVIVLPTGAGKSLVIAELAR-----LARGRVLVLAHVKELVAQ 64

  Fly   117 QIHASQKIMPFPSEDTVQLTGQLPRPKRAELWASKRVFFATPQVVHSDMLEADGECSFPFGSIKL 181
            . ||  |......|..:...|.    ||.|  :..:|.|.:.|.|..::....||.|       |
E. coli    65 N-HA--KYQALGLEADIFAAGL----KRKE--SHGKVVFGSVQSVARNLDAFQGEFS-------L 113

  Fly   182 IVVDEAHRA--KGRYAYTQVADCLMARNRYFRMLALSATPGRTMEDVAAVCRNLYISNL----QV 240
            ::|||.||.  .....|.|:...|...|.:.|:|.|:|||.|..:.        :|...    .|
E. coli   114 LIVDECHRIGDDEESQYQQILTHLTKVNPHLRLLGLTATPFRLGKG--------WIYQFHYHGMV 170

  Fly   241 RWDTSIDVQPYIHRRTIRTIVVSLKERIKEPRERLLQIIEPYLRQLMEAEIFKGNKGTVSRNSLL 305
            |.|.....:..|:...:|.::   |.....|.|||...:..|....::|:    :.|..|...|.
E. coli   171 RGDEKALFRDCIYELPLRYMI---KHGYLTPPERLDMPVVQYDFSRLQAQ----SNGLFSEADLN 228

  Fly   306 FEQKSFVERSAQGQRHPDHNIIMGNFAMCISMYHSLDLME----RHGLRVFVNNFDADDDGREKF 366
            .|.|       :.||...|.|              ..:||    |.|:.:|...
E. coli   229 RELK-------KQQRITPHII--------------SQIMEFAATRKGVMIFAAT----------- 261

  Fly   367 VLARDGNLRNLVEQVRQELGANPLDYTTHAMTNGEVPPLPSDLDFGHAKYEKLR-----QVLVQH 426
                       ||..::.:|..|.:  ..|:..|:.|....|:...:.|.::.|     .||...
E. coli   262 -----------VEHAKEIVGLLPAE--DAALITGDTPGAERDVLIENFKAQRFRYLVNVAVLTTG 313

  Fly   427 FQANPDSRAIVFCEYRESVMLIHRLLLQHRPVLRPRCFVGQGSTVGASYALTQKQQLQIMTDFRS 491
            |.| |....|......|||.|..::                   ||....|...:...::.|: :
E. coli   314 FDA-PHVDLIAILRPTESVSLYQQI-------------------VGRGLRLAPGKTDCLILDY-A 357

  Fly   492 GTSNVLVATSIGEEGLDVGEVEMIVCFDIC---------STNPTRFIQRIGR---------TGRK 538
            |..:.|.|..:|........|.:.|....|         :|.....|:..||         .|.:
E. coli   358 GNPHDLYAPEVGTPKGKSDNVPVQVFCPACGFANTFWGKTTADGTLIEHFGRRCQGWFEDDDGHR 422

  Fly   539 K--------------NGEVVMLVTEGRE--------QQVLKDVLANKDQINKKLLNSSV------ 575
            :              |.|..:.....||        ..:||..|..||.:..:....|:
E. coli   423 EQCDFRFRFKNCPQCNAENDIAARRCRECDTVLVDPDDMLKAALRLKDALVLRCSGMSLQHGHDE 487

  Fly   576 ----VKLSLYEQNPRMVPSKFQPKCEEKHMEPVAEEKPKPKSAAKTKESRKRKQPVAQTGSLRKY 636
                :|::.|:::...|..:|                              |.|..||..:..:.
E. coli   488 KGEWLKITYYDEDGADVSERF------------------------------RLQTPAQRTAFEQL 522

  Fly   637 FKESPPTESQQGILQGIKPYQMSEASQQLVKQQVLR 672
            |..  |.....||     |.:...|:..|.:|.:||
E. coli   523 FIR--PHTRTPGI-----PLRWITAADILAQQALLR 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fancm	NP_650971.2	MPH1	59..>550	CDD:440728	117/543 (22%)
		PTZ00108	<1071..1347	CDD:240271
radD	NP_416689.1	SSL2	3..535	CDD:440681	138/668 (21%)