| Sequence 1: | NP_001262806.1 | Gene: | Fancm / 42543 | FlyBaseID: | FBgn0038889 | Length: | 1489 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055129.2 | Gene: | DDX58 / 23586 | HGNCID: | 19102 | Length: | 925 | Species: | Homo sapiens |
| Alignment Length: | 710 | Identity: | 159/710 - (22%) |
|---|---|---|---|
| Similarity: | 288/710 - (40%) | Gaps: | 164/710 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 8 DDEDLVAALAMHEEQKSEDADGTRWEHCDEACDGF-DMATGHNWIYPNNL--PL--RSYQQTIVQ 67
Fly 68 SAL-FKNTLVVLPTGLGKTFIAAVVMYNFYRWYP---KGKIVFMAPTRPLVSQQIHASQKIMPFP 128
Fly 129 SEDTVQLTG----QLPRPKRAELWASKRVFFATPQVVHSDMLEADGECSFPFGSI-KLIVVDEAH 188
Fly 189 RAKGRYAYTQVADCLMARNRYF------------RMLALSATPG--------RTMEDVAAVCRNL 233
Fly 234 YIS-------NLQV-------------RWDTSI-DVQPYIHRRTIRTIVVSLKERIKEPRERLLQ 277
Fly 278 I------IEPYLRQLMEAEIFKGNKGTVSRNSLLFEQKSFVERSAQGQR---HPDHNIIMGNFAM 333
Fly 334 CIS----MYHSLDLMERHGLRVFVNNFD-ADDDGREKFVLARDGNLRNLVEQVRQELGANPLDYT 393
Fly 394 THAMTNGEVPPLPSDLDFGHAKYEKLRQVLVQHFQANPDSRAIVFCEYRESVMLIHRLLLQHRP- 457
Fly 458 --VLRPRCFVGQGSTVGASYALTQKQQLQIMTDFR-SGTSNVLVATSIGEEGLDVGEVEMIVCFD 519
Fly 520 ICSTNPTRFIQRIGRTGRKKNGEVVMLVTEGREQQVLKDVLANKDQIN---KKLLNSSVVKLSLY 581
Fly 582 EQNPRMVPSKFQPK-----CEEKHMEPVAEEKPKPKSAAKTKE--SRKRKQPVAQTGSLR 634 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Fancm | NP_001262806.1 | MPH1 | 43..608 | CDD:224036 | 139/644 (22%) |
| ResIII | 55..221 | CDD:282678 | 47/198 (24%) | ||
| FANCM_ID | 269..378 | CDD:277190 | 24/122 (20%) | ||
| Helicase_C | 417..539 | CDD:278689 | 36/125 (29%) | ||
| DDX58 | NP_055129.2 | DD | 2..92 | CDD:326335 | |
| CARD_RIG-I_r2 | 100..189 | CDD:260076 | |||
| Interaction with ZC3HAV1. /evidence=ECO:0000269|PubMed:21102435 | 218..925 | 151/680 (22%) | |||
| helicase_insert_domain | 243..771 | CDD:327377 | 132/593 (22%) | ||
| DECH box | 372..375 | 2/2 (100%) | |||
| Mediates interaction with RNF135. /evidence=ECO:0000269|PubMed:23950712 | 735..925 | 24/105 (23%) | |||
| RIG-I_C | 805..918 | CDD:276943 | 6/20 (30%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG1111 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||