Protein Alignment lbe and BARX2

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_003649.2
• Gene: BARX2 / 8538
• HGNCID: 956
• Length: 279
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 74/292 - (25%)
• Similarity: 102/292 - (34%)
• Gaps: 123/292 - (42%)

  Fly   125 KSAIEGVKSFSIADILG-----HSEKQREESVSPPPNANLLAPPASRPIAPSGGLLQPRTEPLDV 184
            |:|....|:|.|.:||.     :.||....||.|    :|:..|  :|:....|....|..||
Human    16 KAARRRYKTFMIDEILSKETCDYFEKLSLYSVCP----SLVVRP--KPLHSCTGSPSLRAYPL-- 72

  Fly   185 HPAAAAAMLLPSGQIVRPWDHLLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRH 249
                 .:::.....::   .||    :|..|.|..||..:          |:.|..:|:|
Human    73 -----LSVITRQPTVI---SHL----VPATPGIAQALSCH----------QVTEAVSAEA----- 110

  Fly   250 MGMNPAIIASEDGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSE-EQPTGSG 313
                                                         .|.|.....:|| ||||
Human   111 ---------------------------------------------PGGEALASSESETEQPT--- 127

  Fly   314 KSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYL 378
                                              |:.||.|:|||.||..|:..|||:|..||||
Human   128 ----------------------------------PRQKKPRRSRTIFTELQLMGLEKKFQKQKYL 158

  Fly   379 SPADRDEIAASLGLSNAQVITWFQNRRAKQKR 410
            |..||.::|.||||:..||.||:||||.|.|:
Human   159 STPDRLDLAQSLGLTQLQVKTWYQNRRMKWKK 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	32/55 (58%)
BARX2	NP_003649.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..137		13/113 (12%)
		Homeodomain	134..190	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..279