DRSC/TRiP Functional Genomics Resources

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Protein Alignment lbe and BARX2

DIOPT Version :9

Sequence 1:NP_524435.2 Gene:lbe / 42542 FlyBaseID:FBgn0011278 Length:479 Species:Drosophila melanogaster
Sequence 2:NP_003649.2 Gene:BARX2 / 8538 HGNCID:956 Length:279 Species:Homo sapiens


Alignment Length:292 Identity:74/292 - (25%)
Similarity:102/292 - (34%) Gaps:123/292 - (42%)


- Green bases have known domain annotations that are detailed below.


  Fly   125 KSAIEGVKSFSIADILG-----HSEKQREESVSPPPNANLLAPPASRPIAPSGGLLQPRTEPLDV 184
            |:|....|:|.|.:||.     :.||....||.|    :|:..|  :|:....|....|..||  
Human    16 KAARRRYKTFMIDEILSKETCDYFEKLSLYSVCP----SLVVRP--KPLHSCTGSPSLRAYPL-- 72

  Fly   185 HPAAAAAMLLPSGQIVRPWDHLLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRH 249
                 .:::.....::   .||    :|..|.|..||..:          |:.|..:|:|     
Human    73 -----LSVITRQPTVI---SHL----VPATPGIAQALSCH----------QVTEAVSAEA----- 110

  Fly   250 MGMNPAIIASEDGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSE-EQPTGSG 313
                                                         .|.|.....:|| ||||   
Human   111 ---------------------------------------------PGGEALASSESETEQPT--- 127

  Fly   314 KSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYL 378
                                              |:.||.|:|||.||..|:..|||:|..||||
Human   128 ----------------------------------PRQKKPRRSRTIFTELQLMGLEKKFQKQKYL 158

  Fly   379 SPADRDEIAASLGLSNAQVITWFQNRRAKQKR 410
            |..||.::|.||||:..||.||:||||.|.|:
Human   159 STPDRLDLAQSLGLTQLQVKTWYQNRRMKWKK 190

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
lbeNP_524435.2 Homeobox 356..410 CDD:395001 31/53 (58%)
BARX2NP_003649.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 110..137 13/113 (12%)
Homeobox 136..189 CDD:306543 31/52 (60%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 194..279
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0488
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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