Protein Alignment lbe and Vax2

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_072159.2
• Gene: Vax2 / 64572
• RGDID: 621133
• Length: 292
• Species: Rattus norvegicus
• Alignment Length: 265
• Identity: 69/265 - (26%)
• Similarity: 109/265 - (41%)
• Gaps: 61/265 - (23%)

  Fly   261 DGSSERS---QRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQK--KKSEEQPTGSGKSNGDT- 319
            ||.:||.   :|.....|.:.|....:.  .|.|....||...::  ..|...|.||.:|.||:
  Rat     3 DGGAERDRGPKRREEPGGRSGCRGEHRG--AEDLRADTGSTSPREIAGTSASSPAGSRESGGDSD 65

  Fly   320 ------PLDALFQMTTKD----FDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLY 374
                  ..|...::..:|    ..|......||:  :||     :::||:||..|::.||..|..
  Rat    66 GQQALGETDHCRRILVRDAKGTIREIVLPKGLDL--DRP-----KRTRTSFTAEQLYRLEMEFQR 123

  Fly   375 QKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAHKSF-------- 431
            .:|:...:|.|:|..|.||..||..||||||.|||:|   ..:|.:.....||.::|
  Rat   124 CQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKD---QSRDLEKRASSSASEAFATSNVLRL 185

  Fly   432 LENVNDLSILKKKPM-------------HESDMVG-----------LAAAAAAAGMVVPVPGSVP 472
            ||....||:.:...:             |....:|           :.:|:|::.:..|:| :|.
  Rat   186 LEQGRLLSVPRAPSLLALSPGLPGLTAGHRGTSLGDPRNSSQRLNPMPSASASSPLPPPLP-AVC 249

  Fly   473 MGGAP 477
            ...||
  Rat   250 FSAAP 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	25/55 (45%)
Vax2	NP_072159.2	vax upstream domain	74..101		5/28 (18%)
		homeobox	102..161		28/66 (42%)
		Homeodomain	103..159	CDD:459649	25/55 (45%)
		vax downstream domain	182..193		2/10 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..241		4/28 (14%)
		vax terminal domain	266..274