Protein Alignment lbe and nkx2.4b

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_571664.1
• Gene: nkx2.4b / 58112
• ZFINID: ZDB-GENE-000830-1
• Length: 307
• Species: Danio rerio
• Alignment Length: 361
• Identity: 81/361 - (22%)
• Similarity: 127/361 - (35%)
• Gaps: 109/361 - (30%)

  Fly   134 FSIADILGHSEKQREESVSPPPNANLLAPPASRPIAPSGGLLQPRTEPLDVHPAAAAAMLLPSGQ 198
            ||::|||...|:..::..:...:|:|.:|...:.......|.|        |..:..|..:|..|
Zfish    11 FSVSDILSPIEETFKKFAAMESSASLASPLYRQSQVSQANLQQ--------HSMSHNAYHMPHSQ 67

  Fly   199 IVRPWDHLLGPTMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASEDGS 263
            .                                .|..:..:.|.   .:..||..|
Zfish    68 F--------------------------------SHSTMGGYCNG---TIGAMGDLP--------- 88

  Fly   264 SERSQRSSSSNGSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTG--SGKSNGDTP-LDALF 325
               |.:.|..||:|             .|...||....:..:..:..|  :|.:.|..| :||..
Zfish    89 ---SYQESMRNGAT-------------ATAWYGSNPEPRYPTISRFMGPSAGMNMGTLPGMDASK 137

  Fly   326 QMTTKDFDESQDKSHLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASL 390
            .|.|.                ...|::||  |..|:..|::|||:||..|||||..:|:.:|:.:
Zfish   138 SMVTL----------------HAAPRRKR--RVLFSQAQVYELERRFKQQKYLSAPEREHLASMI 184

  Fly   391 GLSNAQVITWFQNRRAKQKRDIEELKKDFDSVKVFSAHKSFLENVN--DLSILKK---------- 443
            .|:..||..||||.|.|.||.    .||..|.:..|.:....::..  .|.:|.|
Zfish   185 HLTPTQVKIWFQNHRYKMKRQ----AKDKASQQQDSGNMCAQQSPRRVALPVLVKDGKPCQNGSG 245

  Fly   444 --KPMHE--SDMVGLAAAAAAAGMVVPVPGSVPMGG 475
              .|:|:  ..::|....|:|..:....|....|||
Zfish   246 TPTPIHQQVQSVLGSETLASAEDLEEMSPSPPLMGG 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	25/55 (45%)
nkx2.4b	NP_571664.1	Homeodomain	148..204	CDD:459649	26/57 (46%)