Protein Alignment lbe and BARHL1

DIOPT Version :9

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_064448.1
• Gene: BARHL1 / 56751
• HGNCID: 953
• Length: 327
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 87/320 - (27%)
• Similarity: 128/320 - (40%)
• Gaps: 93/320 - (29%)

  Fly   246 LLRHMGMNPAIIASE----DGSS--ERSQRSSSSNGSTECCSPRQAEK--LEKLTTQEGSEEAQK 302
            :|.|...:||:...:    |..|  |.|.||.|   |::|.||....:  ||..|.:.|......
Human    12 ILSHRAGSPALPKGDPLLGDCRSPLELSPRSES---SSDCSSPASPGRDCLETGTPRPGGASGPG 73

  Fly   303 KKSEEQP----------------------------------TGSGKSNGDTPLDALFQMTTKDFD 333
            ..|..||                                  :.||:.....|...|.....:||.
Human    74 LDSHLQPGQLSAPAQSRTVTSSFLIRDILADCKPLAACAPYSSSGQPAAPEPGGRLAAKAAEDFR 138

  Fly   334 ESQDKS----------------HLDIFSNRPQP----KKKRKSRTAFTNHQIFELEKRFLYQKYL 378
            :..|||                ..:|.|:|..|    ||.||:|||||:||:.:||:.|..||||
Human   139 DKLDKSGSNASSDSEYKVKEEGDREISSSRDSPPVRLKKPRKARTAFTDHQLAQLERSFERQKYL 203

  Fly   379 SPADRDEIAASLGLSNAQVITWFQNRRAKQKR-------------DIEELKKDFDSVKVFSAHKS 430
            |..||.|:||||.|::.||.||:||||.|.||             :...|::.|.|...:.  :|
Human   204 SVQDRMELAASLNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYP--QS 266

  Fly   431 FLENVNDLSIL------------KKKPMHESDMV-GLAAAAAAAGMVVPVPGSVPMGGAP 477
            .:.|::..:.|            .::|:....:: ||..|:.....:.|:.|.:|....|
Human   267 LVSNLDPGAALYLYRGPSAPPPALQRPLVPRILIHGLQGASEPPPPLPPLAGVLPRAAQP 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeobox	356..410	CDD:395001	32/53 (60%)
BARHL1	NP_064448.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..90		22/80 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	112..184		18/71 (25%)
		Homeobox	182..235	CDD:395001	32/52 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..327		5/22 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810