Protein Alignment lbe and BARX1

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_067545.3
• Gene: BARX1 / 56033
• HGNCID: 955
• Length: 254
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 79/309 - (25%)
• Similarity: 107/309 - (34%)
• Gaps: 116/309 - (37%)

  Fly   103 EPRDHTPSPPSAVPEPQTNQTTKSAIEGVKSFSIADILGHSEKQREESVSPPPNANLLAPPASRP 167
            ||......||....:.:.::        .:||.|           ||.::.||.....||.|:
Human     6 EPGAARFGPPEGCADHRPHR--------YRSFMI-----------EEILTEPPGPKGAAPAAA-- 49

  Fly   168 IAPSGGLLQPRTEPLDVHPAAAAAMLLPSGQIVRPWDHLLGPTMPVRPFIPS-ALLHYEQRLALD 231
                               ||||..||..|         :...:..|||... |:|..||...
Human    50 -------------------AAAAGELLKFG---------VQALLAARPFHSHLAVLKAEQAAV-- 84

  Fly   232 YHRQLQEHFNAQAQLLRHMGMNPAIIASEDGSSERSQRSSSSNGSTECCSPRQAEKLEKLTTQEG 296
                    |......|...|::.|::|:..|       ...:.|:...  |.:.:...||
Human    85 --------FKFPLAPLGCSGLSSALLAAGPG-------LPGAAGAPHL--PLELQLRGKL----- 127

  Fly   297 SEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKSHLDIFSNRPQPKKKRKSRTAFT 361
                       :..|.|:..            ||                   .||.|:|||.||
Human   128 -----------EAAGPGEPG------------TK-------------------AKKGRRSRTVFT 150

  Fly   362 NHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNRRAKQKR 410
            ..|:..|||||..|||||..||.::|.|||||..||.||:||||.|.|:
Human   151 ELQLMGLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKK 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	34/55 (62%)
BARX1	NP_067545.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20		4/13 (31%)
		Homeodomain	143..199	CDD:459649	34/55 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..254