Protein Alignment lbe and hoxa5

DIOPT Version :10

• Sequence 1: NP_524435.2
• Gene: lbe / 42542
• FlyBaseID: FBgn0011278
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001011405.1
• Gene: hoxa5 / 496880
• XenbaseID: XB-GENE-486061
• Length: 274
• Species: Xenopus tropicalis
• Alignment Length: 352
• Identity: 83/352 - (23%)
• Similarity: 125/352 - (35%)
• Gaps: 134/352 - (38%)

  Fly    80 AVGNLPEDYFHPLKRLRMSSSSSEPRDHTPSPPSAVPEPQTNQTTKSAIEGVKSFSIADILGHSE 144
            :||....::|         |::...|:: ||.||:..||:.||...||              |
 Frog    55 SVGRSASNHF---------SANDRARNY-PSNPSSSTEPRYNQPAASA--------------H-- 93

  Fly   145 KQREESVSPPPNANLLAPPASRPIAPSGGLLQPRTEPLDVHPAAAAAMLLPSGQIVRPWDHLLGP 209
                   ||||                        :||   |..|.|
 Frog    94 -------SPPP------------------------DPL---PCTAVA------------------ 106

  Fly   210 TMPVRPFIPSALLHYEQRLALDYHRQLQEHFNAQAQLLRHMGMNPAIIASEDGSSERSQRSSSSN 274
            |.||..                                .|.|...:|..|.:.:|..|  :||:.
 Frog   107 TSPVSD--------------------------------SHQGGKNSITNSNNTTSNSS--NSSTG 137

  Fly   275 GSTECCSPRQAEKLEKLTTQEGSEEAQKKKSEEQPTGSGKSNGDTPLDALFQMTTKDFDESQDKS 339
            .||..       ..:.|....|:|:.....|::..:.:.:|...:....::..        ..|.
 Frog   138 TSTHI-------NRDGLGASSGAEDDAPASSDQASSQNSQSPAPSVQPQIYPW--------MRKL 187

  Fly   340 HLDIFSNRPQPKKKRKSRTAFTNHQIFELEKRFLYQKYLSPADRDEIAASLGLSNAQVITWFQNR 404
            |:. ..|...|:.|| :|||:|.:|..||||.|.:.:||:...|.|||.:|.||..|:..|||||
 Frog   188 HIS-HDNIGGPEGKR-ARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNR 250

  Fly   405 RAKQKRDIEELKKDFDSVKVFSAHKSF 431
            |.|.|:| .:||    |:.:.:|..:|
 Frog   251 RMKWKKD-NKLK----SMSMAAAGGAF 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lbe	NP_524435.2	Homeodomain	354..410	CDD:459649	28/55 (51%)
hoxa5	NP_001011405.1	Homeodomain	200..256	CDD:459649	29/56 (52%)